Anomalous Platelet Transport & Fat-Tailed Distributions

21 Jun 2020  ·  Christos Kotsalos, Karim Zouaoui Boudjeltia, Ritabrata Dutta, Jonas Latt, Bastien Chopard ·

The transport of platelets in blood is commonly assumed to obey an advection-diffusion equation. Here we propose a disruptive view, by showing that the random part of their velocity is governed by a fat-tailed probability distribution, usually referred to as a L\'evy flight. Although for small spatio-temporal scales, it is hard to distinguish it from the generally accepted "red blood cell enhanced" Brownian motion, for larger systems this effect is dramatic as the standard approach may underestimate the flux of platelets by several orders of magnitude, compromising in particular the validity of current platelet function tests.

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Computational Physics Biological Physics