Assessment of Multiple-Biomarker Classifiers: fundamental principles and a proposed strategy

30 Oct 2019Waleed A. Yousef

The multiple-biomarker classifier problem and its assessment are reviewed against the background of some fundamental principles from the field of statistical pattern recognition, machine learning, or the recently so-called "data science". A narrow reading of that literature has led many authors to neglect the contribution to the total uncertainty of performance assessment from the finite training sample... (read more)

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