Automated adaptive inference of coarse-grained dynamical models in systems biology

24 Apr 2014Bryan C. DanielsIlya Nemenman

Cellular regulatory dynamics is driven by large and intricate networks of interactions at the molecular scale, whose sheer size obfuscates understanding. In light of limited experimental data, many parameters of such dynamics are unknown, and thus models built on the detailed, mechanistic viewpoint overfit and are not predictive... (read more)

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