cyTRON and cyTRON/JS: two Cytoscape-based applications for the inference of cancer evolution models

8 May 2017Lucrezia PatrunoEdoardo GalimbertiDaniele RamazzottiGiulio CaravagnaLuca De SanoMarco AntoniottiAlex Graudenzi

The increasing availability of sequencing data of cancer samples is fueling the development of algorithmic strategies to investigate tumor heterogeneity and infer reliable models of cancer evolution. We here build up on previous works on cancer progression inference from genomic alteration data, to deliver two distinct Cytoscape-based applications, which allow to produce, visualize and manipulate cancer evolution models, also by interacting with public genomic and proteomics databases... (read more)

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