Development and validation of a novel dementia of Alzheimer's type (DAT) score based on metabolism FDG-PET imaging

2 Nov 2017Karteek PopuriRakesh BalachandarKathryn AlpertDonghuan LuMahadev BhallaIan MackenzieRobin Ging-Yuek HsiungLei WangMirza Faisal Begthe Alzhemier's Disease Neuroimaging Initiative

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer's type (DAT) are used to train a novel multi-scale ensemble classification model. This ensemble model outputs a FDG-PET DAT score (FPDS) between 0 and 1 denoting the probability of a subject to be clinically diagnosed with DAT based on their metabolism profile... (read more)

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