Image-derived generative modeling of pseudo-macromolecular structures - towards the statistical assessment of Electron CryoTomography template matching

12 May 2018Kai Wen WangXiangrui ZengXiaodan LiangZhiguang HuoEric P. XingMin Xu

Cellular Electron CryoTomography (CECT) is a 3D imaging technique that captures information about the structure and spatial organization of macromolecular complexes within single cells, in near-native state and at sub-molecular resolution. Although template matching is often used to locate macromolecules in a CECT image, it is insufficient as it only measures the relative structural similarity... (read more)

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