Large-Scale Unsupervised Deep Representation Learning for Brain Structure

2 May 2018  ·  Ayush Jaiswal, Dong Guo, Cauligi S. Raghavendra, Paul Thompson ·

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted features calculated from different regions of the brain. The construction of such highly specialized features requires a considerable amount of time, manual oversight and careful quality control to ensure the absence of errors in the computational process. Recent advances in Deep Representation Learning have shown great promise in extracting highly non-linear and information-rich features from data. In this paper, we present a novel large-scale deep unsupervised approach to learn generic feature representations of structural brain MRI scans, which requires no specialized domain knowledge or manual intervention. Our method produces low-dimensional representations of brain structure, which can be used to reconstruct brain images with very low error and exhibit performance comparable to FreeSurfer features on various classification tasks.

PDF Abstract
No code implementations yet. Submit your code now

Datasets


  Add Datasets introduced or used in this paper

Results from the Paper


  Submit results from this paper to get state-of-the-art GitHub badges and help the community compare results to other papers.

Methods


No methods listed for this paper. Add relevant methods here