Learning protein constitutive motifs from sequence data

23 Mar 2018 Jérôme Tubiana Simona Cocco Rémi Monasson

Statistical analysis of evolutionary-related protein sequences provides insights about their structure, function, and history. We show that Restricted Boltzmann Machines (RBM), designed to learn complex high-dimensional data and their statistical features, can efficiently model protein families from sequence information... (read more)

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