Map of Life: Measuring and Visualizing Species' Relatedness with "Molecular Distance Maps"

14 Jul 2013Lila KariKathleen A. HillAbu Sadat SayemNathaniel BryansKatelyn DavisNikesh S. Dattani

We propose a novel combination of methods that (i) portrays quantitative characteristics of a DNA sequence as an image, (ii) computes distances between these images, and (iii) uses these distances to output a map wherein each sequence is a point in a common Euclidean space. In the resulting "Molecular Distance Map" each point signifies a DNA sequence, and the geometric distance between any two points reflects the degree of relatedness between the corresponding sequences and species... (read more)

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