medXGAN: Visual Explanations for Medical Classifiers through a Generative Latent Space

11 Apr 2022  ·  Amil Dravid, Florian Schiffers, Boqing Gong, Aggelos K. Katsaggelos ·

Despite the surge of deep learning in the past decade, some users are skeptical to deploy these models in practice due to their black-box nature. Specifically, in the medical space where there are severe potential repercussions, we need to develop methods to gain confidence in the models' decisions. To this end, we propose a novel medical imaging generative adversarial framework, medXGAN (medical eXplanation GAN), to visually explain what a medical classifier focuses on in its binary predictions. By encoding domain knowledge of medical images, we are able to disentangle anatomical structure and pathology, leading to fine-grained visualization through latent interpolation. Furthermore, we optimize the latent space such that interpolation explains how the features contribute to the classifier's output. Our method outperforms baselines such as Gradient-Weighted Class Activation Mapping (Grad-CAM) and Integrated Gradients in localization and explanatory ability. Additionally, a combination of the medXGAN with Integrated Gradients can yield explanations more robust to noise. The code is available at:

PDF Abstract


  Add Datasets introduced or used in this paper

Results from the Paper

  Submit results from this paper to get state-of-the-art GitHub badges and help the community compare results to other papers.


No methods listed for this paper. Add relevant methods here