Wearable technologies are enabling plenty of new applications of computer vision, from life logging to health assistance. Many of them are required to recognize the elements of interest in the scene captured by the camera. This work studies the problem of object detection and localization on videos captured by this type of camera. Wearable videos are a much more challenging scenario for object detection than standard images or even another type of videos, due to lower quality images (e.g. poor focus) or high clutter and occlusion common in wearable recordings. Existing work typically focuses on detecting the objects of focus or those being manipulated by the user wearing the camera. We perform a more general evaluation of the task of object detection in this type of video, because numerous applications, such as marketing studies, also need detecting objects which are not in focus by the user. This work presents a thorough study of the well known YOLO architecture, that offers an excellent trade-off between accuracy and speed, for the particular case of object detection in wearable video. We focus our study on the public ADL Dataset, but we also use additional public data for complementary evaluations. We run an exhaustive set of experiments with different variations of the original architecture and its training strategy. Our experiments drive to several conclusions about the most promising directions for our goal and point us to further research steps to improve detection in wearable videos.