Real-Time Cubature Kalman Filter Parameter Estimation of Blood Pressure Response Characteristics Under Vasoactive Drugs Administration

29 Sep 2019 Tasoujian Shahin Salavati Saeed Grigoriadis Karolos Franchek Matthew

Mathematical modeling and real-time dynamics identification of the mean arterial blood pressure (MAP) response of a patient to vasoactive drug infusion can provide a reliable tool for automated drug administration and therefore, reduce the emergency costs and significantly benefit the patient's MAP regulation in an intensive care unit. To this end, a dynamic first-order linear parameter-varying (LPV) model with varying parameters and varying input delay is considered to capture the MAP response dynamics... (read more)

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