Safety and Robustness in Decision Making: Deep Bayesian Recurrent Neural Networks for Somatic Variant Calling in Cancer

4 Dec 2019Geoffroy Dubourg-FelonneauOmar DarwishChristopher ParsonsDami RebergenJohn W CassidyNirmesh PatelHarry W Clifford

The genomic profile underlying an individual tumor can be highly informative in the creation of a personalized cancer treatment strategy for a given patient; a practice known as precision oncology. This involves next generation sequencing of a tumor sample and the subsequent identification of genomic aberrations, such as somatic mutations, to provide potential candidates of targeted therapy... (read more)

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