SentRNA: Improving computational RNA design by incorporating a prior of human design strategies

8 Mar 2018Jade ShiRhiju DasVijay S. Pande

Solving the RNA inverse folding problem is a critical prerequisite to RNA design, an emerging field in bioengineering with a broad range of applications from reaction catalysis to cancer therapy. Although significant progress has been made in developing machine-based inverse RNA folding algorithms, current approaches still have difficulty designing sequences for large or complex targets... (read more)

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