Simulations of particle tracking in the oligociliated mouse node and implications for left-right symmetry breaking mechanics

30 Sep 2019 Gallagher Meurig T. Montenegro-Johnson Thomas D. Smith David J.

The concept of internal anatomical asymmetry is familiar; usually in humans the heart is on the left and the liver is on the right, however how does the developing embryo know to produce this consistent laterality? Symmetry breaking initiates with left-right asymmetric cilia-driven fluid mechanics in a small fluid-filled structure called the ventral node in mice... (read more)

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