One of the key challenges in Deep Learning is the definition of effective strategies for the detection of adversarial examples.
We introduce the Optimized Gillespie algorithm for simulating Stochastic sPAtial models of Cancer Evolution (OG-SPACE), a computational framework for the simulation of the spatio-temporal evolution of cancer subpopulations and of the experimental procedures of both bulk andsingle-cell sequencing.
By defining a direct acyclic graph representing the composition of activation patterns through the network layers, it is possible to characterize the instances of the input data with respect to both the predicted label and the specific (linear) transformation used to perform predictions.
Compared to other tools, TRaIT supports multi-region and single-cell sequencing data within the same statistical framework, and delivers expressive models that capture many complex evolutionary phenomena.
cyTRON was developed in Java; the code is available at https://github. com/BIMIB-DISCo/cyTRON and on the Cytoscape App Store http://apps. cytoscape. org/apps/cytron.
In this work, we focus on a specific subclass of BNs, named Suppes-Bayes Causal Networks (SBCNs), which include specific structural constraints based on Suppes' probabilistic causation to efficiently model cumulative phenomena.
Several diseases related to cell proliferation are characterized by the accumulation of somatic DNA changes, with respect to wildtype conditions.
Motivation: Driver (epi)genomic alterations underlie the positive selection of cancer subpopulations, which promotes drug resistance and relapse.
The Wivace 2013 Electronic Proceedings in Theoretical Computer Science (EPTCS) contain some selected long and short articles accepted for the presentation at Wivace 2013 - Italian Workshop on Artificial Life and Evolutionary Computation, which was held at the University of Milan-Bicocca, Milan, on the 1st and 2nd of July, 2013.