1 code implementation • 17 Jul 2024 • Finn Behrendt, Debayan Bhattacharya, Robin Mieling, Lennart Maack, Julia Krüger, Roland Opfer, Alexander Schlaefer
Unsupervised Anomaly Detection (UAD) methods rely on healthy data distributions to identify anomalies as outliers.
no code implementations • 14 Jun 2024 • Sarah Grube, Maximilian Neidhardt, Anna-Katarina Herrmann, Johanna Sprenger, Kian Abdolazizi, Sarah Latus, Christian J. Cyron, Alexander Schlaefer
By palpating a tissue with a robot in a minimally invasive fashion force-displacement curves can be acquired.
1 code implementation • 29 Apr 2024 • Debayan Bhattacharya, Finn Behrendt, Benjamin Tobias Becker, Lennart Maack, Dirk Beyersdorff, Elina Petersen, Marvin Petersen, Bastian Cheng, Dennis Eggert, Christian Betz, Anna Sophie Hoffmann, Alexander Schlaefer
Lastly, we fine-tune the encoder part of the 3D CNN on a labelled dataset of normal and anomalous MS images.
1 code implementation • 21 Mar 2024 • Finn Behrendt, Debayan Bhattacharya, Lennart Maack, Julia Krüger, Roland Opfer, Robin Mieling, Alexander Schlaefer
We demonstrate that this ensembling strategy can enhance the performance of DMs and mitigate the sensitivity to different kernel sizes across varying pathologies, highlighting its promise for brain MRI anomaly detection.
no code implementations • 14 Mar 2024 • Maximilian Neidhardt, Robin Mieling, Sarah Latus, Martin Fischer, Tobias Maurer, Alexander Schlaefer
We propose modifying a da~Vinci surgical instrument to realize optical coherence elastography (OCE) for quantitative elasticity estimation.
1 code implementation • 18 Feb 2024 • Debayan Bhattacharya, Konrad Reuter, Finn Behrendt, Lennart Maack, Sarah Grube, Alexander Schlaefer
Our primary novelty lies in PolypNextLSTM, which stands out as the leanest in parameters and the fastest model, surpassing the performance of five state-of-the-art image and video-based deep learning models.
no code implementations • 4 Jan 2024 • Ecem Sogancioglu, Bram van Ginneken, Finn Behrendt, Marcel Bengs, Alexander Schlaefer, Miron Radu, Di Xu, Ke Sheng, Fabien Scalzo, Eric Marcus, Samuele Papa, Jonas Teuwen, Ernst Th. Scholten, Steven Schalekamp, Nils Hendrix, Colin Jacobs, Ward Hendrix, Clara I Sánchez, Keelin Murphy
To address this, we organized a public research challenge, NODE21, aimed at the detection and generation of lung nodules in chest X-rays.
3 code implementations • 7 Dec 2023 • Finn Behrendt, Debayan Bhattacharya, Robin Mieling, Lennart Maack, Julia Krüger, Roland Opfer, Alexander Schlaefer
Using our proposed conditioning mechanism we can reduce the false-positive predictions and enable a more precise delineation of anomalies which significantly enhances the anomaly detection performance compared to established state-of-the-art approaches to unsupervised anomaly detection in brain MRI.
1 code implementation • 30 Jul 2023 • Debesh Jha, Vanshali Sharma, Debapriya Banik, Debayan Bhattacharya, Kaushiki Roy, Steven A. Hicks, Nikhil Kumar Tomar, Vajira Thambawita, Adrian Krenzer, Ge-Peng Ji, Sahadev Poudel, George Batchkala, Saruar Alam, Awadelrahman M. A. Ahmed, Quoc-Huy Trinh, Zeshan Khan, Tien-Phat Nguyen, Shruti Shrestha, Sabari Nathan, Jeonghwan Gwak, Ritika K. Jha, Zheyuan Zhang, Alexander Schlaefer, Debotosh Bhattacharjee, M. K. Bhuyan, Pradip K. Das, Deng-Ping Fan, Sravanthi Parsa, Sharib Ali, Michael A. Riegler, Pål Halvorsen, Thomas de Lange, Ulas Bagci
Automatic analysis of colonoscopy images has been an active field of research motivated by the importance of early detection of precancerous polyps.
1 code implementation • Nature Scientific Reports 2023 • Finn Behrendt, Marcel Bengs, Debayan Bhattacharya, Julia Krüger, Roland Opfer, Alexander Schlaefer
We illustrate how this analysis and a combination of multiple architectures results in state-of-the-art performance for lung nodule detection, which is demonstrated by the proposed model winning the detection track of the Node21 competition.
no code implementations • 12 Jun 2023 • Robin Mieling, Maximilian Neidhardt, Sarah Latus, Carolin Stapper, Stefan Gerlach, Inga Kniep, Axel Heinemann, Benjamin Ondruschka, Alexander Schlaefer
Robotic trajectory guidance has been shown to improve needle positioning, but feedback for real-time navigation is limited.
no code implementations • 26 Apr 2023 • Debayan Bhattacharya, Sarah Latus, Finn Behrendt, Florin Thimm, Dennis Eggert, Christian Betz, Alexander Schlaefer
Needle positioning is essential for various medical applications such as epidural anaesthesia.
no code implementations • 31 Mar 2023 • Debayan Bhattacharya, Finn Behrendt, Benjamin Tobias Becker, Dirk Beyersdorff, Elina Petersen, Marvin Petersen, Bastian Cheng, Dennis Eggert, Christian Betz, Anna Sophie Hoffmann, Alexander Schlaefer
We demonstrate the feasibility of classifying anomalies in the MS. We propose a data enlarging strategy alongside a novel ensembling strategy that proves to be beneficial for paranasal anomaly classification in the MS.
2 code implementations • 7 Mar 2023 • Finn Behrendt, Debayan Bhattacharya, Julia Krüger, Roland Opfer, Alexander Schlaefer
The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets.
no code implementations • 1 Nov 2022 • Debayan Bhattacharya, Finn Behrendt, Benjamin Tobias Becker, Dirk Beyersdorff, Elina Petersen, Marvin Petersen, Bastian Cheng, Dennis Eggert, Christian Betz, Anna Sophie Hoffmann, Alexander Schlaefer
However, experienced clinicians can segregate between normal samples (healthy maxillary sinus) and anomalous samples (anomalous maxillary sinus) after looking at a few normal samples.
no code implementations • 5 Sep 2022 • Debayan Bhattacharya, Benjamin Tobias Becker, Finn Behrendt, Marcel Bengs, Dirk Beyersdorff, Dennis Eggert, Elina Petersen, Florian Jansen, Marvin Petersen, Bastian Cheng, Christian Betz, Alexander Schlaefer, Anna Sophie Hoffmann
Particularly, we use a supervised contrastive loss that encourages embeddings of maxillary sinus volumes with and without anomaly to form two distinct clusters while the cross-entropy loss encourages the 3D CNN to maintain its discriminative ability.
no code implementations • 17 Aug 2022 • Finn Behrendt, Debayan Bhattacharya, Julia Krüger, Roland Opfer, Alexander Schlaefer
Our results show that while the performance between ViTs and CNNs is on par with a small benefit for ViTs, DeiTs outperform the former if a reasonably large data set is available for training.
no code implementations • 12 Apr 2022 • Finn Behrendt, Marcel Bengs, Frederik Rogge, Julia Krüger, Roland Opfer, Alexander Schlaefer
Overall, we highlight the importance of clean data sets for UAD in brain MRI and demonstrate an approach for detecting falsely labeled data directly during training.
no code implementations • 11 Apr 2022 • Maximilian Neidhardt, Marcel Bengs, Sarah Latus, Stefan Gerlach, Christian J. Cyron, Johanna Sprenger, Alexander Schlaefer
The results show that our approach can estimate elastic properties on a pixelwise basis with a mean absolute error of 5. 01+-4. 37 kPa.
no code implementations • 18 Mar 2022 • Sascha Lehmann, Antje Rogalla, Maximilian Neidhardt, Anton Reinecke, Alexander Schlaefer, Sibylle Schupp
Medical cyber-physical systems are safety-critical, and as such, require ongoing verification of their correct behavior, as system failure during run time may cause severe (or even fatal) personal damage.
1 code implementation • 2 Feb 2022 • Max-Heinrich Laves, Malte Tölle, Alexander Schlaefer, Sandy Engelhardt
In POTOBIM, we optimize both the parameters of the prior distribution and the posterior temperature with respect to reconstruction accuracy using Bayesian optimization with Gaussian process regression.
no code implementations • 31 Jan 2022 • Marcel Bengs, Finn Behrendt, Max-Heinrich Laves, Julia Krüger, Roland Opfer, Alexander Schlaefer
We analyze the value of age information during training, as an additional anomaly score, and systematically study several architecture concepts.
no code implementations • 25 Oct 2021 • Sascha Lehmann, Antje Rogalla, Maximilian Neidhardt, Alexander Schlaefer, Sibylle Schupp
Autonomous systems are often applied in uncertain environments, which require prospective action planning and retrospective data evaluation for future planning to ensure safe operation.
no code implementations • 17 Oct 2021 • Debayan Bhattacharya, Christian Betz, Dennis Eggert, Alexander Schlaefer
This is followed by a supervised training on the limited Kvasir-Sessile dataset.
no code implementations • 20 Sep 2021 • Robin Mieling, Johanna Sprenger, Sarah Latus, Lennart Bargsten, Alexander Schlaefer
The distinction between malignant and benign tumors is essential to the treatment of cancer.
no code implementations • 14 Sep 2021 • Marcel Bengs, Satish Pant, Michael Bockmayr, Ulrich Schüller, Alexander Schlaefer
Our top-performing method achieves the AUC-ROC value of 90. 90\% compared to 84. 53\% using the previous approach with smaller input tiles.
no code implementations • 14 Sep 2021 • Marcel Bengs, Finn Behrendt, Julia Krüger, Roland Opfer, Alexander Schlaefer
These methods rely on healthy brain MRIs and eliminate the requirement of pixel-wise annotated data compared to supervised deep learning.
no code implementations • 10 Sep 2021 • Marcel Bengs, Michael Bockmayr, Ulrich Schüller, Alexander Schlaefer
In this work, we propose an end-to-end MB tumor classification and explore transfer learning with various input sizes and matching network dimensions.
no code implementations • 11 Jun 2021 • Max-Heinrich Laves, Malte Tölle, Alexander Schlaefer, Sandy Engelhardt
Bayesian methods feature useful properties for solving inverse problems, such as tomographic reconstruction.
no code implementations • 5 Aug 2020 • Nils Gessert, Julia Krüger, Roland Opfer, Ann-Christin Ostwaldt, Praveena Manogaran, Hagen H. Kitzler, Sven Schippling, Alexander Schlaefer
However, for monitoring disease progression, \textit{lesion activity} in terms of new and enlarging lesions between two time points is a crucial biomarker.
no code implementations • 2 Jul 2020 • Marcel Bengs, Nils Gessert, Wiebke Laffers, Dennis Eggert, Stephan Westermann, Nina A. Mueller, Andreas O. H. Gerstner, Christian Betz, Alexander Schlaefer
We analyze the value of using multiple hyperspectral bands compared to conventional RGB images and we study several machine learning models' ability to make use of the additional spectral information.
no code implementations • 2 Jul 2020 • Marcel Bengs, Nils Gessert, Alexander Schlaefer
Tracking and localizing objects is a central problem in computer-assisted surgery.
1 code implementation • 20 May 2020 • Nils Gessert, Marcel Bengs, Matthias Schlüter, Alexander Schlaefer
Moreover, optical coherence tomography (OCT) and deep learning have been used for estimating forces based on deformation observed in volumetric image data.
no code implementations • MIDL 2019 • Marcel Bengs, Nils Gessert, Alexander Schlaefer
We propose 4D spatio-temporal deep learning for end-to-end motion forecasting and estimation using a stream of OCT volumes.
no code implementations • 21 Apr 2020 • Marcel Bengs, Nils Gessert, Alexander Schlaefer
Autism spectrum disorder (ASD) is associated with behavioral and communication problems.
no code implementations • 21 Apr 2020 • Marcel Bengs, Stephan Westermann, Nils Gessert, Dennis Eggert, Andreas O. H. Gerstner, Nina A. Mueller, Christian Betz, Wiebke Laffers, Alexander Schlaefer
A recent study has shown that hyperspectral imaging (HSI) can be used for non-invasive detection of head and neck tumors, as precancerous or cancerous lesions show specific spectral signatures that distinguish them from healthy tissue.
no code implementations • 21 Apr 2020 • Marcel Bengs, Nils Gessert, Matthias Schlüter, Alexander Schlaefer
For this purpose, we design and evaluate several 3D and 4D deep learning methods and we propose a new deep learning approach.
no code implementations • 20 Apr 2020 • Nils Gessert, Marcel Bengs, Julia Krüger, Roland Opfer, Ann-Christin Ostwaldt, Praveena Manogaran, Sven Schippling, Alexander Schlaefer
While deep learning methods for single-scan lesion segmentation are common, deep learning approaches for lesion activity have only been proposed recently.
no code implementations • MIDL 2019 • Nils Gessert, Marcel Bengs, Julia Krüger, Roland Opfer, Ann-Christin Ostwaldt, Praveena Manogaran, Sven Schippling, Alexander Schlaefer
While deep learning methods for single-scan lesion segmentation are common, deep learning approaches for lesion activity have only been proposed recently.
no code implementations • 25 Jan 2020 • Nils Gessert, Alexander Schlaefer
The ground-truth for the similarity matching scores is determined by a test that aims to capture users' preferences, interests, and attitude that are relevant for forming romantic relationships.
no code implementations • 6 Nov 2019 • Nils Gessert, Marcel Bengs, Alexander Schlaefer
As a result, we propose a recurrent model with state-max-pooling which automatically learns the relevance of different EIS measurements.
1 code implementation • 9 Oct 2019 • Nils Gessert, Maximilian Nielsen, Mohsin Shaikh, René Werner, Alexander Schlaefer
On the official test set our method is ranked first for both tasks with a balanced accuracy of 63. 6% for task 1 and 63. 4% for task 2.
no code implementations • 12 Aug 2019 • Nils Gessert, Alexander Schlaefer
We compare 2D spatial and 3D spatio-temporal CNNs for LV indices regression and cardiac phase classification.
no code implementations • 12 Aug 2019 • Nils Gessert, Martin Gromniak, Marcel Bengs, Lars Matthäus, Alexander Schlaefer
To overcome the time-consuming data annotation, we generate a large number of ground-truth labels using a robotic setup.
no code implementations • 22 May 2019 • Nils Gessert, Torben Priegnitz, Thore Saathoff, Sven-Thomas Antoni, David Meyer, Moritz Franz Hamann, Klaus-Peter Jünemann, Christoph Otte, Alexander Schlaefer
Our novel convGRU-CNN architecture results in the lowest mean absolute error of 1. 59 +- 1. 3 mN and a cross-correlation coefficient of 0. 9997, and clearly outperforms the other methods.
no code implementations • 20 May 2019 • Nils Gessert, Marcel Bengs, Lukas Wittig, Daniel Drömann, Tobias Keck, Alexander Schlaefer, David B. Ellebrecht
For feedback during interventions, real-time in-vivo imaging with confocal laser microscopy has been proposed for differentiation of benign and malignant tissue by manual expert evaluation.
no code implementations • 7 May 2019 • Nils Gessert, Alexander Schlaefer
We propose an efficient approach for NAS in the context of medical, image-based deep learning problems by searching for architectures on low-dimensional data which are subsequently transferred to high-dimensional data.
1 code implementation • 7 May 2019 • Nils Gessert, Thilo Sentker, Frederic Madesta, Rüdiger Schmitz, Helge Kniep, Ivo Baltruschat, René Werner, Alexander Schlaefer
The first problem is the effective use of high-resolution images with pretrained standard architectures for image classification.
no code implementations • 10 Feb 2019 • Nils Gessert, Matthias Schlüter, Sarah Latus, Veronika Volgger, Christian Betz, Alexander Schlaefer
As the results were promising, automatic classification of lesions might be feasible which could assist experts in their decision making.
no code implementations • 19 Jan 2019 • Max-Heinrich Laves, Sarah Latus, Jan Bergmeier, Tobias Ortmaier, Lüder A. Kahrs, Alexander Schlaefer
The resulting volumentric images provide additional information on the shape of caveties in the bone structure, which will be useful for image-to-patient registration and to estimate the drill trajectory.
no code implementations • 4 Dec 2018 • Nils Gessert, Lukas Wittig, Daniel Drömann, Tobias Keck, Alexander Schlaefer, David B. Ellebrecht
Histological evaluation of tissue samples is a typical approach to identify colorectal cancer metastases in the peritoneum.
Cancer Classification Colon Cancer Detection In Confocal Laser Microscopy Images +2
no code implementations • 22 Oct 2018 • Nils Gessert, Sarah Latus, Youssef S. Abdelwahed, David M. Leistner, Matthias Lutz, Alexander Schlaefer
Typically, the scaffold is manually reviewed by an expert, analyzing each of the hundreds of image slices.
no code implementations • 22 Oct 2018 • Nils Gessert, Martin Gromniak, Matthias Schlüter, Alexander Schlaefer
Optical coherence tomography (OCT) is an imaging modality which is used in interventions due to its high spatial resolution of few micrometers and its temporal resolution of potentially several hundred volumes per second.
no code implementations • 13 Aug 2018 • Nils Gessert, Matthias Lutz, Markus Heyder, Sarah Latus, David M. Leistner, Youssef S. Abdelwahed, Alexander Schlaefer
Our results indicate that building a deep learning-based clinical decision support system for plaque detection is feasible.
2 code implementations • 5 Aug 2018 • Nils Gessert, Thilo Sentker, Frederic Madesta, Rüdiger Schmitz, Helge Kniep, Ivo Baltruschat, René Werner, Alexander Schlaefer
We identify heavy class imbalance as a key problem for this challenge and consider multiple balancing approaches such as loss weighting and balanced batch sampling.
no code implementations • 10 Jul 2018 • Omer Rajput, Nils Gessert, Martin Gromniak, Lars Matthäus, Alexander Schlaefer
Head pose estimation and tracking is useful in variety of medical applications.
no code implementations • 30 May 2018 • Nils Gessert, Torben Priegnitz, Thore Saathoff, Sven-Thomas Antoni, David Meyer, Moritz Franz Hamann, Klaus-Peter Jünemann, Christoph Otte, Alexander Schlaefer
Needle insertion is common during minimally invasive interventions such as biopsy or brachytherapy.
no code implementations • 16 May 2018 • Nils Gessert, Markus Heyder, Sarah Latus, David M. Leistner, Youssef S. Abdelwahed, Matthias Lutz, Alexander Schlaefer
Deep learning methods have shown impressive results for a variety of medical problems over the last few years.
no code implementations • 26 Apr 2018 • Nils Gessert, Jens Beringhoff, Christoph Otte, Alexander Schlaefer
Our novel Siamese 3D CNN architecture outperforms single-path methods that achieve a mean average error of 11. 59 +- 6. 7 mN.
no code implementations • 11 Apr 2018 • Nils Gessert, Markus Heyder, Sarah Latus, Matthias Lutz, Alexander Schlaefer
Advanced atherosclerosis in the coronary arteries is one of the leading causes of deaths worldwide while being preventable and treatable.
no code implementations • 10 Mar 2018 • Nils Gessert, Matthias Schlüter, Alexander Schlaefer
We use this setup to provide an in-depth analysis on deep learning-based pose estimation from volumes.