2 code implementations • 23 Mar 2023 • Andrew F. Magee, Andrew J. Holbrook, Jonathan E. Pekar, Itzue W. Caviedes-Solis, Fredrick A. Matsen IV, Guy Baele, Joel O. Wertheim, Xiang Ji, Philippe Lemey, Marc A. Suchard
Phylogenetic and discrete-trait evolutionary inference depend heavily on an appropriate characterization of the underlying character substitution process.
2 code implementations • 2 Jul 2021 • Gabriel W. Hassler, Brigida Gallone, Leandro Aristide, William L. Allen, Max R. Tolkoff, Andrew J. Holbrook, Guy Baele, Philippe Lemey, Marc A. Suchard
Even in the presence of non-trivial phylogenetic model constraints, we show that one may analytically address latent factor uncertainty in a way that (a) aids model flexibility, (b) accelerates computation (by as much as 500-fold) and (c) decreases required tuning.
no code implementations • 3 Mar 2021 • Andrew J. Holbrook, Xiang Ji, Marc A. Suchard
Mutations sometimes increase contagiousness for evolving pathogens.