no code implementations • 29 May 2024 • Shenghuan Sun, Alexander Schubert, Gregory M. Goldgof, Zhiqing Sun, Thomas Hartvigsen, Atul J. Butte, Ahmed Alaa
For this purpose, we propose a new alignment algorithm that uses symbolic representations of clinical reasoning to ground VLMs in medical knowledge.
2 code implementations • 5 Mar 2024 • Brenda Y. Miao, Irene Y. Chen, Christopher YK Williams, Jaysón Davidson, Augusto Garcia-Agundez, Shenghuan Sun, Travis Zack, Suchi Saria, Rima Arnaout, Giorgio Quer, Hossein J. Sadaei, Ali Torkamani, Brett Beaulieu-Jones, Bin Yu, Milena Gianfrancesco, Atul J. Butte, Beau Norgeot, Madhumita Sushil
Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant paradigm shift in how biomedical models can be developed and deployed.
no code implementations • 6 Feb 2024 • Brenda Y. Miao, Christopher YK Williams, Ebenezer Chinedu-Eneh, Travis Zack, Emily Alsentzer, Atul J. Butte, Irene Y. Chen
Notably, we also showed using our approach that "weight gain/mood change" and "insurance coverage" are disproportionately found as reasons for contraceptive switching in specific demographic populations.
no code implementations • 25 Jan 2024 • Madhumita Sushil, Travis Zack, Divneet Mandair, Zhiwei Zheng, Ahmed Wali, Yan-Ning Yu, Yuwei Quan, Atul J. Butte
In this study, we explored whether recent LLMs can reduce the need for large-scale data annotations.
1 code implementation • 7 Aug 2023 • Madhumita Sushil, Vanessa E. Kennedy, Divneet Mandair, Brenda Y. Miao, Travis Zack, Atul J. Butte
Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes.
no code implementations • 16 Jun 2023 • Shenghuan Sun, Travis Zack, Christopher Y. K. Williams, Atul J. Butte, Madhumita Sushil
Our findings indicate that significant disparities exist among breast cancer patients receiving different types of therapies based on social determinants of health.
no code implementations • 16 Jan 2023 • Madhumita Sushil, Atul J. Butte, Ewoud Schuit, Maarten van Smeden, Artuur M. Leeuwenberg
Confirmation is needed with better text mining models, ideally on a larger manually labeled dataset.
no code implementations • 2 Dec 2022 • Shenghuan Sun, Travis Zack, Madhumita Sushil, Atul J. Butte
We used word frequency analysis and Latent Dirichlet Allocation (LDA) topic modeling analysis to characterize this corpus and identify potential topics of discussion.
no code implementations • 12 Oct 2022 • Madhumita Sushil, Dana Ludwig, Atul J. Butte, Vivek A. Rudrapatna
We sought to evaluate the impact of using a domain-specific vocabulary and a large clinical training corpus on the performance of these language models in clinical language inference.
no code implementations • 30 Nov 2018 • Beau Norgeot, Dmytro Lituiev, Benjamin S. Glicksberg, Atul J. Butte
Clinical data for ambulatory care, which accounts for 90% of the nations healthcare spending, is characterized by relatively small sample sizes of longitudinal data, unequal spacing between visits for each patient, with unequal numbers of data points collected across patients.
no code implementations • 24 Jan 2018 • Alvin Rajkomar, Eyal Oren, Kai Chen, Andrew M. Dai, Nissan Hajaj, Peter J. Liu, Xiaobing Liu, Mimi Sun, Patrik Sundberg, Hector Yee, Kun Zhang, Gavin E. Duggan, Gerardo Flores, Michaela Hardt, Jamie Irvine, Quoc Le, Kurt Litsch, Jake Marcus, Alexander Mossin, Justin Tansuwan, De Wang, James Wexler, Jimbo Wilson, Dana Ludwig, Samuel L. Volchenboum, Katherine Chou, Michael Pearson, Srinivasan Madabushi, Nigam H. Shah, Atul J. Butte, Michael Howell, Claire Cui, Greg Corrado, Jeff Dean
Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality.