Search Results for author: Aviv Regev

Found 4 papers, 1 papers with code

Cell types and ontologies of the Human Cell Atlas

no code implementations28 Jun 2021 David Osumi-Sutherland, Chuan Xu, Maria Keays, Peter V. Kharchenko, Aviv Regev, Ed Lein, Sarah A. Teichmann

Massive single-cell profiling efforts have accelerated our discovery of the cellular composition of the human body, while at the same time raising the need to formalise this new knowledge.

Inference of cell dynamics on perturbation data using adjoint sensitivity

1 code implementation13 Apr 2021 Weiqi Ji, Bo Yuan, Ciyue Shen, Aviv Regev, Chris Sander, Sili Deng

While there is no analogous ground truth for real life biological systems, this work demonstrates the ability to construct and parameterize a considerable diversity of network models with high predictive ability.

Reconstructing probabilistic trees of cellular differentiation from single-cell RNA-seq data

no code implementations28 Nov 2018 Miriam Shiffman, William T. Stephenson, Geoffrey Schiebinger, Jonathan Huggins, Trevor Campbell, Aviv Regev, Tamara Broderick

Specifically, we extend the framework of the classical Dirichlet diffusion tree to simultaneously infer branch topology and latent cell states along continuous trajectories over the full tree.

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