no code implementations • 16 Apr 2024 • Ayush Noori, Iñaki Arango, William E. Byrd, Nada Amin
We design a library of 26, 581 novel and diverse small molecules containing hits with high predicted BBB permeability and favorable predicted safety and toxicity profiles, and that could readily be synthesized for experimental validation in the wet lab.
no code implementations • 3 Apr 2024 • ShangHua Gao, Ada Fang, Yepeng Huang, Valentina Giunchiglia, Ayush Noori, Jonathan Richard Schwarz, Yasha Ektefaie, Jovana Kondic, Marinka Zitnik
We envision "AI scientists" as systems capable of skeptical learning and reasoning that empower biomedical research through collaborative agents that integrate AI models and biomedical tools with experimental platforms.
no code implementations • 20 Oct 2023 • Ruth Johnson, Michelle M. Li, Ayush Noori, Owen Queen, Marinka Zitnik
With diverse data -- from patient records to imaging -- GNNs process data holistically by viewing modalities as nodes interconnected by their relationships.
no code implementations • 7 Sep 2022 • Yasha Ektefaie, George Dasoulas, Ayush Noori, Maha Farhat, Marinka Zitnik
Artificial intelligence for graphs has achieved remarkable success in modeling complex systems, ranging from dynamic networks in biology to interacting particle systems in physics.
1 code implementation • 12 Jan 2022 • Tanish Tyagi, Colin G. Magdamo, Ayush Noori, Zhaozhi Li, Xiao Liu, Mayuresh Deodhar, Zhuoqiao Hong, Wendong Ge, Elissa M. Ye, Yi-han Sheu, Haitham Alabsi, Laura Brenner, Gregory K. Robbins, Sahar Zafar, Nicole Benson, Lidia Moura, John Hsu, Alberto Serrano-Pozo, Dimitry Prokopenko, Rudolph E. Tanzi, Bradley T. Hyman, Deborah Blacker, Shibani S. Mukerji, M. Brandon Westover, Sudeshna Das
Dementia related cognitive impairment (CI) is a neurodegenerative disorder, affecting over 55 million people worldwide and growing rapidly at the rate of one new case every 3 seconds.
1 code implementation • 13 Nov 2021 • Tanish Tyagi, Colin G. Magdamo, Ayush Noori, Zhaozhi Li, Xiao Liu, Mayuresh Deodhar, Zhuoqiao Hong, Wendong Ge, Elissa M. Ye, Yi-han Sheu, Haitham Alabsi, Laura Brenner, Gregory K. Robbins, Sahar Zafar, Nicole Benson, Lidia Moura, John Hsu, Alberto Serrano-Pozo, Dimitry Prokopenko, Rudolph E. Tanzi, Bradley T. Hyman, Deborah Blacker, Shibani S. Mukerji, M. Brandon Westover, Sudeshna Das
Automated mining of these notes presents an opportunity to label patients with cognitive impairment in EHR data.
no code implementations • 12 Nov 2020 • Zhuoqiao Hong, Colin G. Magdamo, Yi-han Sheu, Prathamesh Mohite, Ayush Noori, Elissa M. Ye, Wendong Ge, Haoqi Sun, Laura Brenner, Gregory Robbins, Shibani Mukerji, Sahar Zafar, Nicole Benson, Lidia Moura, John Hsu, Bradley T. Hyman, Michael B. Westover, Deborah Blacker, Sudeshna Das
Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data.