Pro-PRIME: A general Temperature-Guided Language model to engineer enhanced Stability and Activity in Proteins

no code implementations • 24 Jul 2023 • Pan Tan, Mingchen Li, Yuanxi Yu, Fan Jiang, Lirong Zheng, Banghao Wu, Xinyu Sun, Liqi Kang, Jie Song, Liang Zhang, Yi Xiong, Wanli Ouyang, Zhiqiang Hu, Guisheng Fan, Yufeng Pei, Liang Hong

Designing protein mutants of both high stability and activity is a critical yet challenging task in protein engineering.

Language Modelling