1 code implementation • 16 Nov 2023 • Aishwarya Mandyam, Matthew Jörke, William Denton, Barbara E. Engelhardt, Emma Brunskill
Tailoring advice to a person's unique goals, preferences, and life circumstances is a critical component of health coaching that has been underutilized in adaptive algorithms for mobile health interventions.
1 code implementation • 14 Jun 2023 • Michael Minyi Zhang, Gregory W. Gundersen, Barbara E. Engelhardt
The Gaussian process latent variable model (GPLVM) is a popular probabilistic method used for nonlinear dimension reduction, matrix factorization, and state-space modeling.
1 code implementation • 13 Mar 2023 • Aishwarya Mandyam, Didong Li, Diana Cai, Andrew Jones, Barbara E. Engelhardt
In this work, we incorporate existing domain-specific data to achieve better posterior concentration rates.
1 code implementation • 13 Oct 2021 • Guillaume Martinet, Alexander Strzalkowski, Barbara E. Engelhardt
Selecting powerful predictors for an outcome is a cornerstone task for machine learning.
1 code implementation • 12 Oct 2021 • F. William Townes, Barbara E. Engelhardt
Gaussian processes are widely used for the analysis of spatial data due to their nonparametric flexibility and ability to quantify uncertainty, and recently developed scalable approximations have facilitated application to massive datasets.
1 code implementation • 26 Mar 2021 • Gregory W. Gundersen, Diana Cai, Chuteng Zhou, Barbara E. Engelhardt, Ryan P. Adams
We propose a multi-fidelity approach that makes cost-sensitive decisions about which data fidelity to collect based on maximizing information gain with respect to changepoints.
2 code implementations • 19 Jun 2020 • Gregory W. Gundersen, Michael Minyi Zhang, Barbara E. Engelhardt
By approximating a nonlinear relationship between the latent space and the observations with a function that is linear with respect to random features, we induce closed-form gradients of the posterior distribution with respect to the latent variable.
1 code implementation • 17 Mar 2020 • Allison J. B. Chaney, Archit Verma, Young-suk Lee, Barbara E. Engelhardt
This uniquely allows NDMs both to deconvolve each observation into its constituent factors, and also to describe how the factor distributions specific to each observation vary across observations and deviate from the corresponding global factors.
1 code implementation • 11 Oct 2019 • Federico Camerlenghi, Bianca Dumitrascu, Federico Ferrari, Barbara E. Engelhardt, Stefano Favaro
The problem of maximizing cell type discovery under budget constraints is a fundamental challenge for the collection and analysis of single-cell RNA-sequencing (scRNA-seq) data.
Applications
no code implementations • 1 Jun 2019 • Li-Fang Cheng, Bianca Dumitrascu, Michael Zhang, Corey Chivers, Michael Draugelis, Kai Li, Barbara E. Engelhardt
However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains challenging.
no code implementations • 30 May 2019 • Niranjani Prasad, Barbara E. Engelhardt, Finale Doshi-Velez
A key impediment to reinforcement learning (RL) in real applications with limited, batch data is defining a reward function that reflects what we implicitly know about reasonable behaviour for a task and allows for robust off-policy evaluation.
1 code implementation • 24 May 2019 • Michael Minyi Zhang, Bianca Dumitrascu, Sinead A. Williamson, Barbara E. Engelhardt
Many machine learning problems can be framed in the context of estimating functions, and often these are time-dependent functions that are estimated in real-time as observations arrive.
no code implementations • 14 Aug 2018 • Li-Fang Cheng, Niranjani Prasad, Barbara E. Engelhardt
There exists an inherent trade-off in the selection and timing of lab tests between considerations of the expected utility in clinical decision-making of a given test at a specific time, and the associated cost or risk it poses to the patient.
no code implementations • NeurIPS 2018 • Bianca Dumitrascu, Karen Feng, Barbara E. Engelhardt
We address the problem of regret minimization in logistic contextual bandits, where a learner decides among sequential actions or arms given their respective contexts to maximize binary rewards.
no code implementations • 30 Oct 2017 • Allison J. B. Chaney, Brandon M. Stewart, Barbara E. Engelhardt
Recommendation systems are ubiquitous and impact many domains; they have the potential to influence product consumption, individuals' perceptions of the world, and life-altering decisions.
1 code implementation • 30 May 2017 • Vladimir Feinberg, Li-Fang Cheng, Kai Li, Barbara E. Engelhardt
Gaussian processes (GPs), or distributions over arbitrary functions in a continuous domain, can be generalized to the multi-output case: a linear model of coregionalization (LMC) is one approach.
no code implementations • 20 Apr 2017 • Niranjani Prasad, Li-Fang Cheng, Corey Chivers, Michael Draugelis, Barbara E. Engelhardt
The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units.
1 code implementation • 27 Mar 2017 • Li-Fang Cheng, Gregory Darnell, Bianca Dumitrascu, Corey Chivers, Michael E Draugelis, Kai Li, Barbara E. Engelhardt
In the scenario of real-time monitoring of hospital patients, high-quality inference of patients' health status using all information available from clinical covariates and lab tests is essential to enable successful medical interventions and improve patient outcomes.
no code implementations • 9 Jan 2017 • Mehmet E. Basbug, Barbara E. Engelhardt
We present a general framework, the coupled compound Poisson factorization (CCPF), to capture the missing-data mechanism in extremely sparse data sets by coupling a hierarchical Poisson factorization with an arbitrary data-generating model.
no code implementations • 17 Aug 2016 • Ghassen Jerfel, Mehmet E. Basbug, Barbara E. Engelhardt
Model-based collaborative filtering analyzes user-item interactions to infer latent factors that represent user preferences and item characteristics in order to predict future interactions.
no code implementations • 13 Apr 2016 • Mehmet E. Basbug, Barbara E. Engelhardt
Here, we introduce hierarchical compound Poisson factorization (HCPF) that has the favorable Gamma-Poisson structure and scalability of HPF to high-dimensional extremely sparse matrices.
no code implementations • 17 Mar 2016 • Shiwen Zhao, Barbara E. Engelhardt, Sayan Mukherjee, David B. Dunson
We illustrate the utility of our approach on simulated data, comparing results from MELD to alternative methods, and we show the promise of our approach through the application of MELD to several data sets.
no code implementations • 16 Feb 2016 • Jordan T. Ash, Robert E. Schapire, Barbara E. Engelhardt
Domain adaptation addresses the problem created when training data is generated by a so-called source distribution, but test data is generated by a significantly different target distribution.
1 code implementation • 8 Dec 2015 • Ashlee Valente, Geoffrey Ginsburg, Barbara E. Engelhardt
Genome-wide association studies have proven to be essential for understanding the genetic basis of disease.
no code implementations • 13 Apr 2015 • Gregory Darnell, Stoyan Georgiev, Sayan Mukherjee, Barbara E. Engelhardt
In this paper we develop an approach for dimension reduction that exploits the assumption of low rank structure in high dimensional data to gain both computational and statistical advantages.
1 code implementation • 11 Nov 2014 • Shiwen Zhao, Chuan Gao, Sayan Mukherjee, Barbara E. Engelhardt
Latent factor models are the canonical statistical tool for exploratory analyses of low-dimensional linear structure for an observation matrix with p features across n samples.
no code implementations • 7 Nov 2014 • Chuan Gao, Shiwen Zhao, Ian C. McDowell, Christopher D. Brown, Barbara E. Engelhardt
Further, we develop a method to recover gene co-expression networks from the estimated sparse biclustering matrices.
1 code implementation • 17 Oct 2013 • Chuan Gao, Christopher D. Brown, Barbara E. Engelhardt
To address this problem, we developed a Bayesian sparse latent factor model that uses a three parameter beta prior to flexibly model shrinkage in the loading matrix.
Applications Genomics