no code implementations • 13 Aug 2024 • Gizem Mert, Ario Sadafi, Raheleh Salehi, Nassir Navab, Carsten Marr
Biomedical imaging and RNA sequencing with single-cell resolution improves our understanding of white blood cell diseases like leukemia.
no code implementations • 8 Apr 2024 • Michael Deutges, Ario Sadafi, Nassir Navab, Carsten Marr
We test our approach on three datasets of white blood cell images and show that we achieve competitive performance compared to conventional methods.
1 code implementation • 7 Apr 2024 • Valentin Koch, Sophia J. Wagner, Salome Kazeminia, Ece Sancar, Matthias Hehr, Julia Schnabel, Tingying Peng, Carsten Marr
In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears.
1 code implementation • 21 Mar 2024 • Xudong Sun, Carla Feistner, Alexej Gossmann, George Schwarz, Rao Muhammad Umer, Lisa Beer, Patrick Rockenschaub, Rahul Babu Shrestha, Armin Gruber, Nutan Chen, Sayedali Shetab Boushehri, Florian Buettner, Carsten Marr
DomainLab is a modular Python package for training user specified neural networks with composable regularization loss terms.
1 code implementation • 20 Mar 2024 • Xudong Sun, Nutan Chen, Alexej Gossmann, Yu Xing, Carla Feistner, Emilio Dorigatt, Felix Drost, Daniele Scarcella, Lisa Beer, Carsten Marr
We address the online combinatorial choice of weight multipliers for multi-objective optimization of many loss terms parameterized by neural works via a probabilistic graphical model (PGM) for the joint model parameter and multiplier evolution process, with a hypervolume based likelihood promoting multi-objective descent.
no code implementations • 8 Mar 2024 • Salome Kazeminia, Max Joosten, Dragan Bosnacki, Carsten Marr
Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training.
1 code implementation • 9 Jan 2024 • Benedikt Roth, Valentin Koch, Sophia J. Wagner, Julia A. Schnabel, Carsten Marr, Tingying Peng
Recently, foundation models in computer vision showed that leveraging huge amounts of data through supervised or self-supervised learning improves feature quality and generalizability for a variety of tasks.
no code implementations • 5 Sep 2023 • Yu Liu, Gesine Muller, Nassir Navab, Carsten Marr, Jan Huisken, Tingying Peng
Light-sheet fluorescence microscopy (LSFM), a planar illumination technique that enables high-resolution imaging of samples, experiences defocused image quality caused by light scattering when photons propagate through thick tissues.
no code implementations • 24 Aug 2023 • Ario Sadafi, Raheleh Salehi, Armin Gruber, Sayedali Shetab Boushehri, Pascal Giehr, Nassir Navab, Carsten Marr
Here, we propose a rehearsal-based continual learning approach for class incremental and domain incremental scenarios in white blood cell classification.
no code implementations • 24 Aug 2023 • Ario Sadafi, Matthias Hehr, Nassir Navab, Carsten Marr
To that end, we train multiple MIL models using different levels of sex imbalance in the training set and excluding certain age groups.
no code implementations • 26 Jul 2023 • Salome Kazeminia, Carsten Marr, Bastian Rieck
In biomedical data analysis, Multiple Instance Learning (MIL) models have emerged as a powerful tool to classify patients' microscopy samples.
1 code implementation • 15 Mar 2023 • Ario Sadafi, Oleksandra Adonkina, Ashkan Khakzar, Peter Lienemann, Rudolf Matthias Hehr, Daniel Rueckert, Nassir Navab, Carsten Marr
Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making.
no code implementations • 14 Mar 2023 • Rao Muhammad Umer, Armin Gruber, Sayedali Shetab Boushehri, Christian Metak, Carsten Marr
Here, we train a robust CNN for WBC classification by addressing cross-domain data imbalance and domain shifts.
no code implementations • 2 Mar 2023 • Ario Sadafi, Nassir Navab, Carsten Marr
Querying the expert to annotate regions of interest in a WSI guides the formation of high-attention regions for MIL.
no code implementations • 2 Mar 2023 • Daniel Sens, Ario Sadafi, Francesco Paolo Casale, Nassir Navab, Carsten Marr
Recent MIL approaches produce highly informative bag level representations by utilizing the transformer architecture's ability to model the dependencies between instances.
1 code implementation • 30 Aug 2022 • Dominik J. E. Waibel, Ernst Röell, Bastian Rieck, Raja Giryes, Carsten Marr
Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution.
1 code implementation • 4 Jul 2022 • Salome Kazeminia, Ario Sadafi, Asya Makhro, Anna Bogdanova, Shadi Albarqouni, Carsten Marr
Deep learning-based classification of rare anemia disorders is challenged by the lack of training data and instance-level annotations.
1 code implementation • 1 Jul 2022 • Raheleh Salehi, Ario Sadafi, Armin Gruber, Peter Lienemann, Nassir Navab, Shadi Albarqouni, Carsten Marr
Here, we propose a cross-domain adapted autoencoder to extract features in an unsupervised manner on three different datasets of single white blood cells scanned from peripheral blood smears.
no code implementations • 27 Jun 2022 • Yu Liu, Kurt Weiss, Nassir Navab, Carsten Marr, Jan Huisken, Tingying Peng
Light-sheet fluorescence microscopy (LSFM) is a cutting-edge volumetric imaging technique that allows for three-dimensional imaging of mesoscopic samples with decoupled illumination and detection paths.
1 code implementation • 3 Mar 2022 • Dominik J. E. Waibel, Scott Atwell, Matthias Meier, Carsten Marr, Bastian Rieck
We propose to complement geometrical shape information by including multi-scale topological features, such as connected components, cycles, and voids, in the reconstruction loss.
no code implementations • 11 Sep 2021 • Ario Sadafi, Asya Makhro, Leonid Livshits, Nassir Navab, Anna Bogdanova, Shadi Albarqouni, Carsten Marr
Sickle cell disease (SCD) is a severe genetic hemoglobin disorder that results in premature destruction of red blood cells.
1 code implementation • 26 Jul 2021 • Sophia J. Wagner, Nadieh Khalili, Raghav Sharma, Melanie Boxberg, Carsten Marr, Walter de Back, Tingying Peng
Alternatively, color augmentation can be applied during training leading to a more robust model without the extra step of color normalization at test time.
1 code implementation • 17 Mar 2021 • Ario Sadafi, Lucía María Moya Sans, Asya Makhro, Leonid Livshits, Nassir Navab, Anna Bogdanova, Shadi Albarqouni, Carsten Marr
Hereditary hemolytic anemias are genetic disorders that affect the shape and density of red blood cells.
1 code implementation • BMC Bioinformatics 2021 • Dominik J. E. Waibel, Sayedali Shetab Boushehri, Carsten Marr
InstantDL enables researchers with a basic computational background to apply debugged and benchmarked state-of-the-art deep learning algorithms to their own data with minimal effort.
1 code implementation • 22 Jul 2020 • Ario Sadafi, Asya Makhro, Anna Bogdanova, Nassir Navab, Tingying Peng, Shadi Albarqouni, Carsten Marr
In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis.