1 code implementation • 26 Sep 2023 • Vik Shirvaikar, Chris Holmes
Treatment effect heterogeneity (TEH), or variability in treatment effect for different subgroups within a population, is of significant interest in clinical trial analysis.
no code implementations • 11 Jul 2023 • Jack Jewson, Sahra Ghalebikesabi, Chris Holmes
To ameliorate this, we propose $\beta$D-Bayes, a posterior sampling scheme from a generalised posterior targeting the minimisation of the $\beta$-divergence between the model and the data generating process.
1 code implementation • 26 Jun 2023 • Lucile Ter-Minassian, Oscar Clivio, Karla Diaz-Ordaz, Robin J. Evans, Chris Holmes
We introduce Path-Wise Shapley effects (PWSHAP), a framework for assessing the targeted effect of a binary (e. g.~treatment) variable from a complex outcome model.
1 code implementation • 31 May 2023 • Christopher Williams, Fabian Falck, George Deligiannidis, Chris Holmes, Arnaud Doucet, Saifuddin Syed
U-Nets are a go-to, state-of-the-art neural architecture across numerous tasks for continuous signals on a square such as images and Partial Differential Equations (PDE), however their design and architecture is understudied.
no code implementations • 4 Apr 2023 • Robin Mitra, Sarah F. McGough, Tapabrata Chakraborti, Chris Holmes, Ryan Copping, Niels Hagenbuch, Stefanie Biedermann, Jack Noonan, Brieuc Lehmann, Aditi Shenvi, Xuan Vinh Doan, David Leslie, Ginestra Bianconi, Ruben Sanchez-Garcia, Alisha Davies, Maxine Mackintosh, Eleni-Rosalina Andrinopoulou, Anahid Basiri, Chris Harbron, Ben D. MacArthur
Missing data are an unavoidable complication in many machine learning tasks.
no code implementations • 19 Jan 2023 • Fabian Falck, Christopher Williams, Dominic Danks, George Deligiannidis, Christopher Yau, Chris Holmes, Arnaud Doucet, Matthew Willetts
U-Net architectures are ubiquitous in state-of-the-art deep learning, however their regularisation properties and relationship to wavelets are understudied.
1 code implementation • 17 Jan 2023 • Rob Cornish, Muhammad Faaiz Taufiq, Arnaud Doucet, Chris Holmes
Digital twins hold substantial promise in many applications, but rigorous procedures for assessing their accuracy are essential for their widespread deployment in safety-critical settings.
no code implementations • 15 Dec 2022 • Davide Pigoli, Kieran Baker, Jobie Budd, Lorraine Butler, Harry Coppock, Sabrina Egglestone, Steven G. Gilmour, Chris Holmes, David Hurley, Radka Jersakova, Ivan Kiskin, Vasiliki Koutra, Jonathon Mellor, George Nicholson, Joe Packham, Selina Patel, Richard Payne, Stephen J. Roberts, Björn W. Schuller, Ana Tendero-Cañadas, Tracey Thornley, Alexander Titcomb
Since early in the coronavirus disease 2019 (COVID-19) pandemic, there has been interest in using artificial intelligence methods to predict COVID-19 infection status based on vocal audio signals, for example cough recordings.
1 code implementation • 15 Dec 2022 • Harry Coppock, George Nicholson, Ivan Kiskin, Vasiliki Koutra, Kieran Baker, Jobie Budd, Richard Payne, Emma Karoune, David Hurley, Alexander Titcomb, Sabrina Egglestone, Ana Tendero Cañadas, Lorraine Butler, Radka Jersakova, Jonathon Mellor, Selina Patel, Tracey Thornley, Peter Diggle, Sylvia Richardson, Josef Packham, Björn W. Schuller, Davide Pigoli, Steven Gilmour, Stephen Roberts, Chris Holmes
Recent work has reported that AI classifiers trained on audio recordings can accurately predict severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection status.
1 code implementation • 15 Dec 2022 • Jobie Budd, Kieran Baker, Emma Karoune, Harry Coppock, Selina Patel, Ana Tendero Cañadas, Alexander Titcomb, Richard Payne, David Hurley, Sabrina Egglestone, Lorraine Butler, Jonathon Mellor, George Nicholson, Ivan Kiskin, Vasiliki Koutra, Radka Jersakova, Rachel A. McKendry, Peter Diggle, Sylvia Richardson, Björn W. Schuller, Steven Gilmour, Davide Pigoli, Stephen Roberts, Josef Packham, Tracey Thornley, Chris Holmes
The UK COVID-19 Vocal Audio Dataset represents the largest collection of SARS-CoV-2 PCR-referenced audio recordings to date.
no code implementations • 13 Jun 2022 • Sahra Ghalebikesabi, Chris Holmes, Edwin Fong, Brieuc Lehmann
In the context of density estimation, the standard nonparametric Bayesian approach is to target the posterior predictive of the Dirichlet process mixture model.
1 code implementation • 1 Mar 2022 • Oscar Clivio, Fabian Falck, Brieuc Lehmann, George Deligiannidis, Chris Holmes
We leverage these balancing scores to perform matching for high-dimensional causal inference and call this procedure neural score matching.
no code implementations • 1 Feb 2022 • Natalia Garcia Martin, Stefano Malacrino, Marta Wojciechowska, Leticia Campo, Helen Jones, David C. Wedge, Chris Holmes, Korsuk Sirinukunwattana, Heba Sailem, Clare Verrill, Jens Rittscher
Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions.
no code implementations • 24 Aug 2021 • Sahra Ghalebikesabi, Harrison Wilde, Jack Jewson, Arnaud Doucet, Sebastian Vollmer, Chris Holmes
Increasing interest in privacy-preserving machine learning has led to new and evolved approaches for generating private synthetic data from undisclosed real data.
1 code implementation • NeurIPS 2021 • Sahra Ghalebikesabi, Lucile Ter-Minassian, Karla Diaz-Ordaz, Chris Holmes
Empirically, we observe that Neighbourhood Shapley values identify meaningful sparse feature relevance attributions that provide insight into local model behaviour, complimenting conventional Shapley analysis.
1 code implementation • NeurIPS 2021 • Fabian Falck, Haoting Zhang, Matthew Willetts, George Nicholson, Christopher Yau, Chris Holmes
Work in deep clustering focuses on finding a single partition of data.
1 code implementation • 5 Mar 2021 • Sahra Ghalebikesabi, Rob Cornish, Luke J. Kelly, Chris Holmes
We propose a variational autoencoder architecture to model both ignorable and nonignorable missing data using pattern-set mixtures as proposed by Little (1993).
1 code implementation • 13 Feb 2021 • Alexander Camuto, Xiaoyu Wang, Lingjiong Zhu, Chris Holmes, Mert Gürbüzbalaban, Umut Şimşekli
In this paper we focus on the so-called `implicit effect' of GNIs, which is the effect of the injected noise on the dynamics of SGD.
no code implementations • 16 Nov 2020 • Harrison Wilde, Jack Jewson, Sebastian Vollmer, Chris Holmes
There is significant growth and interest in the use of synthetic data as an enabler for machine learning in environments where the release of real data is restricted due to privacy or availability constraints.
no code implementations • 14 Jul 2020 • Matthew Willetts, Xenia Miscouridou, Stephen Roberts, Chris Holmes
Successfully training Variational Autoencoders (VAEs) with a hierarchy of discrete latent variables remains an area of active research.
no code implementations • NeurIPS 2020 • Alexander Camuto, Matthew Willetts, Umut Şimşekli, Stephen Roberts, Chris Holmes
We study the regularisation induced in neural networks by Gaussian noise injections (GNIs).
no code implementations • 14 Jul 2020 • Alexander Camuto, Matthew Willetts, Stephen Roberts, Chris Holmes, Tom Rainforth
We make inroads into understanding the robustness of Variational Autoencoders (VAEs) to adversarial attacks and other input perturbations.
no code implementations • 9 Jul 2020 • Tom Lovett, Mark Briers, Marcos Charalambides, Radka Jersakova, James Lomax, Chris Holmes
The Covid-19 pandemic has resulted in a variety of approaches for managing infection outbreaks in international populations.
1 code implementation • NeurIPS 2021 • Sheheryar Zaidi, Arber Zela, Thomas Elsken, Chris Holmes, Frank Hutter, Yee Whye Teh
On a variety of classification tasks and modern architecture search spaces, we show that the resulting ensembles outperform deep ensembles not only in terms of accuracy but also uncertainty calibration and robustness to dataset shift.
no code implementations • 18 Feb 2020 • Alexander Camuto, Matthew Willetts, Brooks Paige, Chris Holmes, Stephen Roberts
Separating high-dimensional data like images into independent latent factors, i. e independent component analysis (ICA), remains an open research problem.
no code implementations • 25 Sep 2019 • Matthew Willetts, Stephen Roberts, Chris Holmes
In clustering we normally output one cluster variable for each datapoint.
no code implementations • 25 Sep 2019 • Matthew Willetts, Alexander Camuto, Stephen Roberts, Chris Holmes
This paper is concerned with the robustness of VAEs to adversarial attacks.
no code implementations • 25 Sep 2019 • Matthew Willetts, Alexander Camuto, Stephen Roberts, Chris Holmes
We develop a new method for regularising neural networks.
no code implementations • ICLR 2021 • Matthew Willetts, Alexander Camuto, Tom Rainforth, Stephen Roberts, Chris Holmes
We make significant advances in addressing this issue by introducing methods for producing adversarially robust VAEs.
no code implementations • 21 May 2019 • Edwin Fong, Chris Holmes
In Bayesian statistics, the marginal likelihood, also known as the evidence, is used to evaluate model fit as it quantifies the joint probability of the data under the prior.
1 code implementation • 8 Feb 2019 • Edwin Fong, Simon Lyddon, Chris Holmes
Increasingly complex datasets pose a number of challenges for Bayesian inference.
no code implementations • 21 Dec 2018 • Sebastian Vollmer, Bilal A. Mateen, Gergo Bohner, Franz J. Király, Rayid Ghani, Pall Jonsson, Sarah Cumbers, Adrian Jonas, Katherine S. L. McAllister, Puja Myles, David Granger, Mark Birse, Richard Branson, Karel GM Moons, Gary S Collins, John P. A. Ioannidis, Chris Holmes, Harry Hemingway
Machine learning (ML), artificial intelligence (AI) and other modern statistical methods are providing new opportunities to operationalize previously untapped and rapidly growing sources of data for patient benefit.
1 code implementation • 29 Oct 2018 • Matthew Willetts, Aiden Doherty, Stephen Roberts, Chris Holmes
We introduce 'semi-unsupervised learning', a problem regime related to transfer learning and zero-shot learning where, in the training data, some classes are sparsely labelled and others entirely unlabelled.
1 code implementation • ICML 2018 • Tammo Rukat, Chris Holmes, Christopher Yau
Boolean tensor decomposition approximates data of multi-way binary relationships as product of interpretable low-rank binary factors, following the rules Boolean algebra.
no code implementations • 22 Sep 2017 • Simon Lyddon, Chris Holmes, Stephen Walker
In this paper we revisit the weighted likelihood bootstrap, a method that generates samples from an approximate Bayesian posterior of a parametric model.
1 code implementation • 11 May 2015 • Rémi Bardenet, Arnaud Doucet, Chris Holmes
Finally, we have only been able so far to propose subsampling-based methods which display good performance in scenarios where the Bernstein-von Mises approximation of the target posterior distribution is excellent.