Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression.
no code implementations • 11 Oct 2019 • Okyaz Eminaga, Yuri Tolkach, Christian Kunder, Mahmood Abbas, Ryan Han, Rosalie Nolley, Axel Semjonow, Martin Boegemann, Sebastian Huss, Andreas Loening, Robert West, Geoffrey Sonn, Richard Fan, Olaf Bettendorf, James Brook, Daniel Rubin
For case usage, these models were applied for the annotation tasks in clinician-oriented pathology reports for prostatectomy specimens.
A well-fitted PlexusNet-based model delivered comparable classification performance (AUC: 0. 963) in distinguishing prostate cancer from healthy tissues, although it was at least 23 times smaller, had a better model calibration and clinical utility than the comparison models.