Deciphering the unique dynamic activation pathway in a G protein-coupled receptor enables unveiling biased signaling and identifying cryptic allosteric sites in conformational intermediates

no code implementations • 24 Apr 2025 • Jigang Fan, Chunhao Zhu, Xiaobing Lan, Haiming Zhuang, Mingyu Li, Jian Zhang, Shaoyong Lu

Neurotensin receptor 1 (NTSR1), a member of the Class A G protein-coupled receptor superfamily, plays an important role in modulating dopaminergic neuronal activity and eliciting opioid-independent analgesia.

Are We Ready for Service Robots? The OpenLORIS-Scene Datasets for Lifelong SLAM

no code implementations • 13 Nov 2019 • Xuesong Shi, Dongjiang Li, Pengpeng Zhao, Qinbin Tian, Yuxin Tian, Qiwei Long, Chunhao Zhu, Jingwei Song, Fei Qiao, Le Song, Yangquan Guo, Zhigang Wang, Yimin Zhang, Baoxing Qin, Wei Yang, Fangshi Wang, Rosa H. M. Chan, Qi She

We also design benchmarking metrics for lifelong SLAM, with which the robustness and accuracy of pose estimation are evaluated separately.

Benchmarking Pose Estimation +1