Search Results for author: Elisabeth G. Rens

Found 3 papers, 0 papers with code

Cellular tango: How extracellular matrix adhesion choreographs Rac-Rho signaling and cell movement

no code implementations19 Apr 2021 Elisabeth G. Rens, Leah Edelstein-Keshet

The small GTPases Rac and Rho are known to regulate eukaryotic cell shape, promoting front protrusion (Rac) or rear retraction (Rho) of the cell edge.

Spots, strips, and spiral waves in models for static and motile cells

no code implementations23 Sep 2019 Yue Liu, Elisabeth G. Rens, Leah Edelstein-Keshet

The polarization and motility of eukaryotic cells depends on assembly and contraction of the actin cytoskeleton and its regulation by proteins called GTPases.

Cell Shape and Durotaxis Follow from Mechanical Cell-Substrate Reciprocity and Focal Adhesion Dynamics: A Unifying Mathematical Model

no code implementations21 Jun 2019 Elisabeth G. Rens, Roeland M. H. Merks

Many animal cells change their shape depending on the stiffness of the substrate on which they are cultured: they assume small, rounded shapes in soft ECMs, they elongate within stiffer ECMs, and flatten out on hard substrates.

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