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In vivo optogenetic identification and manipulation of GABAergic interneuron subtypes
Identification and manipulation of different GABAergic interneuron classes in the behaving animal are important to understand their role in circuit dynamics and behavior.
Bidirectional optogenetic control of inhibitory neurons in freely-moving mice
To create a multi-color/multi-site optoelectronic device, a four-shank silicon probe mounted on a microdrive was equipped with two dual-color and two single-color units, for a total weight under 3 g. Devices were implanted in mice expressing the blue-light sensitive cation channel ChR2 and the red-light sensitive chloride pump Jaws in parvalbumin-immunoreactive (PV) inhibitory neurons.
Outan: An On-Head System for Driving micro-LED Arrays Implanted in Freely Moving Mice
In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation.
