Search Results for author: Federico Bocci

Found 3 papers, 0 papers with code

Stochastic fluctuations promote ordered pattern formation of cells in the Notch-Delta signaling pathway

no code implementations1 Feb 2022 Madeline Galbraith, Federico Bocci, José N. Onuchic

The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells.

Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response

no code implementations16 Apr 2019 Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly, Jose N. Onuchic, Herbert Levine

In this review, we first discuss recent efforts combining theoretical and experimental approaches to elucidate mechanisms underlying EMT multi-stability (i. e. the existence of multiple stable phenotypes during EMT) and the properties of hybrid E/M phenotypes.

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