Label-free virtual HER2 immunohistochemical staining of breast tissue using deep learning

no code implementations • 8 Dec 2021 • Bijie Bai, Hongda Wang, Yuzhu Li, Kevin De Haan, Francesco Colonnese, Yujie Wan, Jingyi Zuo, Ngan B. Doan, Xiaoran Zhang, Yijie Zhang, Jingxi Li, Wenjie Dong, Morgan Angus Darrow, Elham Kamangar, Han Sung Lee, Yair Rivenson, Aydogan Ozcan

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation of pathogenesis.

Generative Adversarial Network whole slide images