Search Results for author: George M. Church

Found 4 papers, 1 papers with code

Variational auto-encoding of protein sequences

2 code implementations9 Dec 2017 Sam Sinai, Eric Kelsic, George M. Church, Martin A. Nowak

Here we present an embedding of natural protein sequences using a Variational Auto-Encoder and use it to predict how mutations affect protein function.

Rosetta Brains: A Strategy for Molecularly-Annotated Connectomics

no code implementations21 Apr 2014 Adam H. Marblestone, Evan R Daugharthy, Reza Kalhor, Ian D Peikon, Justus M Kebschull, Seth L Shipman, Yuriy Mishchenko, Je Hyuk Lee, Konrad P. Kording, Edward S. Boyden, Anthony M Zador, George M. Church

We propose a neural connectomics strategy called Fluorescent In-Situ Sequencing of Barcoded Individual Neuronal Connections (FISSEQ-BOINC), leveraging fluorescent in situ nucleic acid sequencing in fixed tissue (FISSEQ).

Neurons and Cognition

Physical Principles for Scalable Neural Recording

no code implementations24 Jun 2013 Adam H. Marblestone, Bradley M. Zamft, Yael G. Maguire, Mikhail G. Shapiro, Thaddeus R. Cybulski, Joshua I. Glaser, Dario Amodei, P. Benjamin Stranges, Reza Kalhor, David A. Dalrymple, Dongjin Seo, Elad Alon, Michel M. Maharbiz, Jose M. Carmena, Jan M. Rabaey, Edward S. Boyden, George M. Church, Konrad P. Kording

Simultaneously measuring the activities of all neurons in a mammalian brain at millisecond resolution is a challenge beyond the limits of existing techniques in neuroscience.

Neurons and Cognition Biological Physics

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