Search Results for author: Helena U. Zacharias

Found 4 papers, 3 papers with code

BITES: Balanced Individual Treatment Effect for Survival data

1 code implementation5 Jan 2022 Stefan Schrod, Andreas Schäfer, Stefan Solbrig, Robert Lohmayer, Wolfram Gronwald, Peter J. Oefner, Tim Beißbarth, Rainer Spang, Helena U. Zacharias, Michael Altenbuchinger

Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatment, and not for alternative treatments (the so-called counterfactual outcomes).

DRAGON: Determining Regulatory Associations using Graphical models on multi-Omic Networks

1 code implementation4 Apr 2021 Katherine H. Shutta, Deborah Weighill, Rebekka Burkholz, Marouen Ben Guebila, Dawn L. DeMeo, Helena U. Zacharias, John Quackenbush, Michael Altenbuchinger

The increasing quantity of multi-omics data, such as methylomic and transcriptomic profiles, collected on the same specimen, or even on the same cell, provide a unique opportunity to explore the complex interactions that define cell phenotype and govern cellular responses to perturbations.

Scale-invariant biomarker discovery in urine and plasma metabolite fingerprints

1 code implementation22 Mar 2017 Helena U. Zacharias, Thorsten Rehberg, Sebastian Mehrl, Daniel Richtmann, Tilo Wettig, Peter J. Oefner, Rainer Spang, Wolfram Gronwald, Michael Altenbuchinger

Motivation: Metabolomics data is typically scaled to a common reference like a constant volume of body fluid, a constant creatinine level, or a constant area under the spectrum.


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