Search Results for author: Herbert Levine

Found 7 papers, 0 papers with code

Epigenetic factor competition reshapes the EMT landscape

no code implementations13 Sep 2022 M. Ali Al-Radhawi, Shubham Tripathi, Yun Zhang, Eduardo D. Sontag, Herbert Levine

In such models, epigenetic factors are usually proposed to act on the chromatin regions directly involved in the expression of relevant genes.

Mathematical Modeling of Plasticity and Heterogeneity in EMT

no code implementations25 Jul 2019 Shubham Tripathi, Jianhua Xing, Herbert Levine, Mohit Kumar Jolly

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels.

Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response

no code implementations16 Apr 2019 Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly, Jose N. Onuchic, Herbert Levine

In this review, we first discuss recent efforts combining theoretical and experimental approaches to elucidate mechanisms underlying EMT multi-stability (i. e. the existence of multiple stable phenotypes during EMT) and the properties of hybrid E/M phenotypes.

Ordered Hexagonal Patterns via Notch-Delta Signaling

no code implementations13 Feb 2019 Eial Teomy, David A. Kessler, Herbert Levine

Many developmental processes in biology utilize Notch-Delta signaling to construct an ordered pattern of cellular differentiation.

Eshel Ben-Jacob: A unique individual in the science of collective phenomena

no code implementations18 Mar 2018 Herbert Levine

Eshel Ben-Jacob, one of the co-organizers of this meeting on collective behavior and one of the pioneers in the field of collective behavior in biology, passed away suddenly just before we convened.

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