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Interpretable Droplet Digital PCR Assay for Trustworthy Molecular Diagnostics
Droplet digital PCR (ddPCR) has emerged as a gold standard for achieving absolute quantification.
Advancements in Programmable Lipid Nanoparticles: Exploring the Four-Domain Model for Targeted Drug Delivery
Programmable lipid nanoparticles, or LNPs, represent a breakthrough in the realm of targeted drug delivery, offering precise spatiotemporal control essential for the treatment of complex diseases such as cancer and genetic disorders.
Artificial Intelligence Enhanced Digital Nucleic Acid Amplification Testing for Precision Medicine and Molecular Diagnostics
The precise quantification of nucleic acids is pivotal in molecular biology, underscored by the rising prominence of nucleic acid amplification tests (NAAT) in diagnosing infectious diseases and conducting genomic studies.
SAM-dPCR: Real-Time and High-throughput Absolute Quantification of Biological Samples Using Zero-Shot Segment Anything Model
This accessible, cost-effective tool transcends the limitations of traditional detection methods or fully supervised AI models, marking the first application of SAM in nucleic acid detection or molecular diagnostics.
Auto-ICell: An Accessible and Cost-Effective Integrative Droplet Microfluidic System for Real-Time Single-Cell Morphological and Apoptotic Analysis
The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis.
Deep Learning Approach for Large-Scale, Real-Time Quantification of Green Fluorescent Protein-Labeled Biological Samples in Microreactors
Absolute quantification of biological samples entails determining expression levels in precise numerical copies, offering enhanced accuracy and superior performance for rare templates.
Targeted Sub-attomole Cancer Biomarker Detection based on Phase Singularity 2D Nanomaterial-enhanced Plasmonic Biosensor
By precisely engineering the configuration with atomically thin materials, the phase singularity has been successfully achieved with a significantly enhanced lateral position shift effect.
Applied Physics Instrumentation and Detectors Medical Physics Optics
