no code implementations • 1 Nov 2019 • Rishi Mukhopadhyay, Paul Shealy, Homayoun Valafar
Despite many advances in computational modeling of protein structures, these methods have not been widely utilized by experimental structural biologists.
no code implementations • 6 Nov 2019 • Ryan Yandle, Rishi Mukhopadhyay, Homayoun Valafar
The method of Probability Density Profile Analysis has been introduced previously as a tool to find the best match between a set of experimentally generated Residual Dipolar Couplings and a set of known protein structures.
no code implementations • 19 Nov 2019 • Casey A Cole, Caleb Parks, Julian Rachele, Homayoun Valafar
Traditional approaches to elucidation of protein structures by NMR spectroscopy rely on distance restraints also known as nuclear Overhauser effects (NOEs).
no code implementations • 25 Nov 2019 • Brendan E. Odigwe, Jesuloluwa S. Eyitayo, Celestine I. Odigwe, Homayoun Valafar
While Hydroxyurea reduces the complications associated with Sickle Cell Anemia in some patients, others do not benefit from this drug and experience deleterious effects since it is also a chemotherapeutic agent.
no code implementations • 12 Dec 2019 • Liang Zhao, Brendan Odigwe, Susan Lessner, Daniel G. Clair, Firas Mussa, Homayoun Valafar
We report an object tracking algorithm that combines geometrical constraints, thresholding, and motion detection for tracking of the descending aorta and the network of major arteries that branch from the aorta including the iliac and femoral arteries.
no code implementations • 12 Dec 2019 • Nicholas Boltin, Daniel Vu, Bethany Janos, Alyssa Shofner, Joan Culley, Homayoun Valafar
In this report we examine the effectiveness of WISER in identification of a chemical culprit during a chemical based Mass Casualty Incident (MCI).
no code implementations • 7 Jan 2020 • Chrisogonas O. Odhiambo, Casey A. Cole, Alaleh Torkjazi, Homayoun Valafar
The use of sensors has pervaded everyday life in several applications including human activity monitoring, healthcare, and social networks.
no code implementations • 9 Jan 2020 • Hanin Omar, Casey A. Cole, Arjang Fahim, Giuliana Gusmaroli, Stephen Borgianini, Homayoun Valafar
High-throughput cDNA sequencing (RNA-seq) is a very powerful technique to quantify gene expression in an unbiased way.
1 code implementation • 5 Mar 2020 • Casey A. Cole, Bethany Janos, Dien Anshari, James F. Thrasher, Scott Strayer, Homayoun Valafar
Diseases resulting from prolonged smoking are the most common preventable causes of death in the world today.
no code implementations • 23 Jul 2020 • Niharika Pandala, Casey A. Cole, Devaun McFarland, Anita Nag, Homayoun Valafar
Recent events leading to the worldwide pandemic of COVID-19 have demonstrated the effective use of genomic sequencing technologies to establish the genetic sequence of this virus.
no code implementations • 30 Jul 2020 • Homayoun Valafar, Faramarz Valafar, Okan Ersoy
The architecture has all the advantages of the previous models such as self-organization and possesses some other superior characteristics such as input parallelism and decision making based on consensus.
no code implementations • 30 Jul 2020 • Faramarz Valafar, Homayoun Valafar, William S. York
Proton nuclear magnetic resonance (1H-NMR) is a widely used tool for chemical structural analysis.
no code implementations • 31 Jul 2020 • Faramarz Valafar, Homayoun Valafar
The developed system is implemented on the world wide web, and is intended to identify PMAAs using submitted spectra of these molecules recorded on any GC-EIMS instrument.
no code implementations • 2 Aug 2020 • Aaron Hein, Casey Cole, Homayoun Valafar
Our investigations concluded that one-hot encoding, the use of LSTMs, and window sizes of 9, 11, and 15 produce the optimal outcome.
no code implementations • 12 Dec 2020 • Xijiang Miao, Michael G. Bryson, Homayoun Valafar
This article introduces a novel protein structure alignment method (named TALI) based on the protein backbone torsion angle instead of the more traditional distance matrix.
no code implementations • 16 Dec 2020 • Homayoun Valafar, Faramarz Valafar
Analysis of 1H-NMR spectra is often hindered by large variations that occur during the collection of these spectra.
no code implementations • 19 May 2021 • Chrisogonas Odhiambo, Pamela Wright, Cindy Corbett, Homayoun Valafar
Poor medication adherence presents serious economic and health problems including compromised treatment effectiveness, medical complications, and loss of billions of dollars in wasted medicine or procedures.
no code implementations • 13 Sep 2021 • Brendan E. Odigwe, Francis G. Spinale, Homayoun Valafar
We have demonstrated that using machine learning approaches can identify HF patients with a high probability of a positive CRT response (95% accuracy), and of equal importance, identify those HF patients that would not derive a functional benefit from CRT.
no code implementations • 4 Nov 2021 • Andrew Smith, Hardik Anand, Snezana Milosavljevic, Katherine M. Rentschler, Ana Pocivavsek, Homayoun Valafar
Here we have shown the potential of various machine learning classifiers to automatically, accurately, and reliably classify vigilance states based on a single EEG reading and a single EMG reading.
no code implementations • 1 Apr 2022 • Nicholas D. Boltin, Joan M. Culley, Homayoun Valafar
Chemical Mass Casualty Incidents (MCI) place a heavy burden on hospital staff and resources.
no code implementations • 3 Jun 2022 • Chrisogonas O. Odhiambo, Sanjoy Saha, Corby K. Martin, Homayoun Valafar
The use of sensors available through smart devices has pervaded everyday life in several applications including human activity monitoring, healthcare, and social networks.
no code implementations • 1 Feb 2023 • Ali Firooz, Avery T. Funkhouser, Julie C. Martin, W. Jeffery Edenfield, Homayoun Valafar, Anna V. Blenda
Nuanced cancer patient care is needed, as the development and clinical course of cancer is multifactorial with influences from the general health status of the patient, germline and neoplastic mutations, co-morbidities, and environment.
no code implementations • 5 Apr 2023 • Arjang Fahim, Stephanie Irausquin, Homayoun Valafar
Despite the recent advances in various Structural Genomics Projects, a large gap remains between the number of sequenced and structurally characterized proteins.
no code implementations • 29 Aug 2023 • Lexington Whalen, Nathan Bickel, Shash Comandur, Dalton Craven, Stanley Dubinsky, Homayoun Valafar
It is estimated that 85% of people in juvenile delinquent systems cannot adequately read or write, that more than half of those with substance abuse issues have complications in reading or writing and that two-thirds of those who do not complete high school lack proper literacy skills.
1 code implementation • 17 Nov 2023 • Alireza Bagheri Rajeoni, Breanna Pederson, Ali Firooz, Hamed Abdollahi, Andrew K. Smith, Daniel G. Clair, Susan M. Lessner, Homayoun Valafar
Pathological alterations in the human vascular system underlie many chronic diseases, such as atherosclerosis and aneurysms.
1 code implementation • 27 Nov 2023 • Alireza Bagheri Rajeoni, Breanna Pederson, Daniel G. Clair, Susan M. Lessner, Homayoun Valafar
However, manual analysis of CTA images is time-consuming and tedious.