no code implementations • 30 Jun 2022 • Tairan Liu, Yuzhu Li, Hatice Ceylan Koydemir, Yijie Zhang, Ethan Yang, Merve Eryilmaz, Hongda Wang, Jingxi Li, Bijie Bai, Guangdong Ma, Aydogan Ozcan
We also demonstrated that this data-driven plaque assay offers the capability of quantifying the infected area of the cell monolayer, performing automated counting and quantification of PFUs and virus-infected areas over a 10-fold larger dynamic range of virus concentration than standard viral plaque assays.
no code implementations • 7 May 2022 • Yuzhu Li, Tairan Liu, Hatice Ceylan Koydemir, Hongda Wang, Keelan O'Riordan, Bijie Bai, Yuta Haga, Junji Kobashi, Hitoshi Tanaka, Takaya Tamaru, Kazunori Yamaguchi, Aydogan Ozcan
Due to the large scalability, ultra-large field-of-view, and low cost of the TFT-based image sensors, this platform can be integrated with each agar plate to be tested and disposed of after the automated CFU count.
no code implementations • 8 Dec 2021 • Bijie Bai, Hongda Wang, Yuzhu Li, Kevin De Haan, Francesco Colonnese, Yujie Wan, Jingyi Zuo, Ngan B. Doan, Xiaoran Zhang, Yijie Zhang, Jingxi Li, Wenjie Dong, Morgan Angus Darrow, Elham Kamangar, Han Sung Lee, Yair Rivenson, Aydogan Ozcan
The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation of pathogenesis.
no code implementations • 22 Dec 2020 • Xilin Yang, Luzhe Huang, Yilin Luo, Yichen Wu, Hongda Wang, Yair Rivenson, Aydogan Ozcan
We present a virtual image refocusing method over an extended depth of field (DOF) enabled by cascaded neural networks and a double-helix point-spread function (DH-PSF).
no code implementations • 1 Jul 2020 • Tairan Liu, Kevin de Haan, Bijie Bai, Yair Rivenson, Yi Luo, Hongda Wang, David Karalli, Hongxiang Fu, Yibo Zhang, John FitzGerald, Aydogan Ozcan
Our analysis shows that a trained deep neural network can extract the birefringence information using both the sample specific morphological features as well as the holographic amplitude and phase distribution.
no code implementations • 29 Jan 2020 • Hongda Wang, Hatice Ceylan Koydemir, Yunzhe Qiu, Bijie Bai, Yibo Zhang, Yiyin Jin, Sabiha Tok, Enis Cagatay Yilmaz, Esin Gumustekin, Yair Rivenson, Aydogan Ozcan
Our experiments further confirmed that this method successfully detects 90% of bacterial colonies within 7-10 h (and >95% within 12 h) with a precision of 99. 2-100%, and correctly identifies their species in 7. 6-12 h with 80% accuracy.
Cultural Vocal Bursts Intensity Prediction General Classification
1 code implementation • 31 Jan 2019 • Yichen Wu, Yair Rivenson, Hongda Wang, Yilin Luo, Eyal Ben-David, Laurent A. Bentolila, Christian Pritz, Aydogan Ozcan
Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes.
no code implementations • 30 Mar 2018 • Yair Rivenson, Hongda Wang, Zhensong Wei, Yibo Zhang, Harun Gunaydin, Aydogan Ozcan
Here, we demonstrate a label-free approach to create a virtually-stained microscopic image using a single wide-field auto-fluorescence image of an unlabeled tissue sample, bypassing the standard histochemical staining process, saving time and cost.
no code implementations • 12 Dec 2017 • Yair Rivenson, Hatice Ceylan Koydemir, Hongda Wang, Zhensong Wei, Zhengshuang Ren, Harun Gunaydin, Yibo Zhang, Zoltan Gorocs, Kyle Liang, Derek Tseng, Aydogan Ozcan
Mobile-phones have facilitated the creation of field-portable, cost-effective imaging and sensing technologies that approach laboratory-grade instrument performance.
no code implementations • 12 May 2017 • Yair Rivenson, Zoltan Gorocs, Harun Gunaydin, Yibo Zhang, Hongda Wang, Aydogan Ozcan
We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field.