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Found 18 papers, 2 papers with code
Seizure freedom after surgical resection of diffusion-weighted MRI abnormalities
Current clinical approaches to identify structural abnormalities for surgical targeting in epilepsy do not use diffusion-weighted MRI (dMRI), despite evidence that dMRI abnormalities are present in epilepsy and may relate to the epileptogenic zone.
Anti-seizure medication load is not correlated with early termination of seizure spread
Our objective was to test if this effect was due to limiting seizure spread through early termination of otherwise unchanged seizures.
Status epilepticus and thinning of the entorhinal cortex
Individuals with TLE and SE had reduced entorhinal thickness compared to those with TLE and no history of SE.
The Imaging Database for Epilepsy And Surgery (IDEAS)
To demonstrate the veracity of our data, we successfully replicated previous studies showing long-term outcomes of seizure freedom in the range of around 50%.
Anti-seizure medication tapering correlates with daytime delta band power reduction in the cortex
The finding of decreased ${\delta}$ band power during ASM tapering agrees with previous literature.
Alpha rhythm slowing in temporal epilepsy across Scalp EEG and MEG
Alpha slowing in TLE was found in both EEG and MEG recordings.
Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra
Combining periodic and aperiodic abnormalities improved performance, similar to the complete band power approach.
Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo
Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expression of biological rhythms in the brain.
Identifying epileptogenic abnormalities through spatial clustering of MEG interictal band power
We quantified the spatial overlap between the abnormality cluster and subsequent resection, hypothesising a greater overlap in seizure-free patients.
Interictal MEG abnormalities to guide intracranial electrode implantation and predict surgical outcome
Finally, we assessed if the implantation of electrodes in abnormal tissue, and resection of the strongest abnormalities determined by MEG and iEEG explained surgical outcome.
Normative brain mapping using scalp EEG and potential clinical application
Scalp EEG relative band power normative maps are spatially stable across time, in keeping with MEG and intracranial EEG results.
Complementary structural and functional abnormalities to localise epileptogenic tissue
Here, we investigate whether structural connectivity abnormalities, inferred from dMRI, may be used in conjunction with functional iEEG abnormalities to aid localisation and resection of the epileptogenic zone (EZ), and improve surgical outcomes in epilepsy.
Temporal stability of intracranial EEG abnormality maps for localising epileptogenic tissue
To assess the localising value of band power abnormality, we computed DRS - a measure of how different the surgically resected and spared tissue were in terms of band power abnormalities - over time.
Effects of anterior temporal lobe resection on cortical morphology
Here, we examine the effects of this surgery on cortical morphology measured in independent variables both near the resection and remotely.
MEG abnormalities and mechanisms of surgical failure in neocortical epilepsy
Resting-state MEG data were acquired for 70 healthy controls and 32 patients with refractory neocortical epilepsy.
Intracranial EEG structure-function coupling predicts surgical outcomes in focal epilepsy
We investigated pre-operative structure-function coupling at two spatial scales a) at the global iEEG network level and b) at the resolution of individual iEEG electrode contacts using virtual surgeries.
Volumetric and structural connectivity abnormalities co-localise in TLE
We computed grey matter volumetric changes and white matter structural connectivity abnormalities in 144 patients with unilateral TLE and 96 healthy controls.
Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue
We then compared interictal recordings from 62 patients with epilepsy to the normative map to identify abnormal regions.
