Search Results for author: Jianhua Xing

Found 5 papers, 0 papers with code

Cell phenotypic transition proceeds through concerted reorganization of gene regulatory network

no code implementations8 Jul 2021 Weikang Wang, Dante Poe, Ke Ni, Jianhua Xing

Phenotype transition takes place in many biological processes such as differentiation, and understanding how a cell reprograms its global gene expression profile is a problem of rate theories.

Mathematical Modeling of Plasticity and Heterogeneity in EMT

no code implementations25 Jul 2019 Shubham Tripathi, Jianhua Xing, Herbert Levine, Mohit Kumar Jolly

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels.

Biophysics at the coffee shop: lessons learned working with George Oster

no code implementations20 Feb 2019 Oleg Igoshin, Jing Chen, Jianhua Xing, Jian Liu, Timothy C. Elston, Michael Grabe, Kenneth S. Kim, Jasmine Nirody, Padmini Rangamani, Sean Sun, Hongyun Wang, Charles Wolgemuth

Over the past 50 years, the use of mathematical models, derived from physical reasoning, to describe molecular and cellular systems has evolved from an art of the few to a cornerstone of biological inquiry.

Physical Intuition

Spatial clustering and common regulatory elements correlate with coordinated gene expression

no code implementations18 Jan 2019 Jingyu Zhang, HengYu Chen, Ruoyan Li, David A. Taft, Guang Yao, Fan Bai, Jianhua Xing

Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes.

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