no code implementations • 3 Sep 2024 • Nathan Evans, Sarah J. Gascoigne, Guillermo M. Besne, Chris Thornton, Gabrielle M. Schroeder, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Peter N. Taylor, Yujiang Wang
Our objective was to test if this effect was due to limiting seizure spread through early termination of otherwise unchanged seizures.
no code implementations • 10 Jun 2024 • Peter N. Taylor, Yujiang Wang, Callum Simpson, Vytene Janiukstyte, Jonathan Horsley, Karoline Leiberg, Beth Little, Harry Clifford, Sophie Adler, Sjoerd B. Vos, Gavin P Winston, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, John S Duncan
To demonstrate the veracity of our data, we successfully replicated previous studies showing long-term outcomes of seizure freedom in the range of around 50%.
no code implementations • 3 Jun 2024 • Bethany Little, Nida Alyas, Alexander Surtees, Gavin P Winston, John S Duncan, David A Cousins, John-Paul Taylor, Peter Taylor, Karoline Leiberg, Yujiang Wang
Finally, with the ability to investigate multiple morphology measures in the same framework, we found that biological covariates are better explained in specific morphology measures, and for clinical applications, only some measures are sensitive to the disease process.
1 code implementation • 2 May 2024 • Guillermo M. Besne, Nathan Evans, Mariella Panagiotopoulou, Billy Smith, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Mathew Walker, Peter N. Taylor, Chris Thornton, Yujiang Wang
Anti-seizure medications (ASMs) are the primary treatment for epilepsy, yet medication tapering effects have not been investigated in a dose, region, and time-dependent manner, despite their potential impact on research and clinical practice.
no code implementations • 16 Apr 2024 • Vytene Janiukstyte, Csaba Kozma, Thomas W. Owen, Umair J Chaudhury, Beate Diehl, Louis Lemieux, John S Duncan, Fergus Rugg-Gunn, Jane de Tisi, Yujiang Wang, Peter N. Taylor
Alpha slowing in TLE was found in both EEG and MEG recordings.
no code implementations • 13 Sep 2023 • Christopher Thornton, Mariella Panagiotopoulou, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Sarah J Gascoigne, Guillermo Besne, Andrew W McEvoy, Anna Miserocchi, Billy C Smith, Jane de Tisi, Peter N Taylor, Yujiang Wang
Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expression of biological rhythms in the brain.
no code implementations • 6 Apr 2023 • Vytene Janiukstyte, Thomas W Owen, Umair J Chaudhary, Beate Diehl, Louis Lemieux, John S Duncan, Jane de Tisi, Yujiang Wang, Peter N Taylor
Scalp EEG relative band power normative maps are spatially stable across time, in keeping with MEG and intracranial EEG results.
no code implementations • 6 Apr 2023 • Jonathan J Horsley, Rhys H Thomas, Fahmida A Chowdhury, Beate Diehl, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Sjoerd B Vos, Matthew C Walker, Gavin P Winston, John S Duncan, Yujiang Wang, Peter N Taylor
Here, we investigate whether structural connectivity abnormalities, inferred from dMRI, may be used in conjunction with functional iEEG abnormalities to aid localisation and resection of the epileptogenic zone (EZ), and improve surgical outcomes in epilepsy.
no code implementations • 11 Feb 2023 • Yujiang Wang, Gabrielle M Schroeder, Jonathan J Horsley, Mariella Panagiotopoulou, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Peter N Taylor
To assess the localising value of band power abnormality, we computed DRS - a measure of how different the surgically resected and spared tissue were in terms of band power abnormalities - over time.
1 code implementation • 13 Dec 2022 • Karoline Leiberg, Jane de Tisi, John S Duncan, Bethany Little, Peter N Taylor, Sjoerd B Vos, Gavin P Winston, Bruno Mota, Yujiang Wang
Here, we examine the effects of this surgery on cortical morphology measured in independent variables both near the resection and remotely.
no code implementations • 10 May 2021 • Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen, Gabrielle M Schroeder, Frances E Hutchings, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Sjoerd B Vos, Matthew C Walker, Yujiang Wang
We then compared interictal recordings from 62 patients with epilepsy to the normative map to identify abnormal regions.