Aperiodic MEG abnormality in patients with focal to bilateral tonic-clonic seizures

no code implementations • 18 Oct 2023 • Kirandeep Kaur, Jonathan J Horsley, Csaba Kozma, Gerard R Hall, Thomas W Owen, Yujiang Wang, Guarav Singh, Sarat P Chandra, Manjari Tripathi, Peter N Taylor

Here, we hypothesised greater aperiodic abnormality in the epileptogenic zone, in patients with focal to bilateral tonic clonic (FBTC) seizures, and earlier age of seizure onset.

Complementary structural and functional abnormalities to localise epileptogenic tissue

no code implementations • 6 Apr 2023 • Jonathan J Horsley, Rhys H Thomas, Fahmida A Chowdhury, Beate Diehl, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Sjoerd B Vos, Matthew C Walker, Gavin P Winston, John S Duncan, Yujiang Wang, Peter N Taylor

Here, we investigate whether structural connectivity abnormalities, inferred from dMRI, may be used in conjunction with functional iEEG abnormalities to aid localisation and resection of the epileptogenic zone (EZ), and improve surgical outcomes in epilepsy.

EEG

Temporal stability of intracranial EEG abnormality maps for localising epileptogenic tissue

no code implementations • 11 Feb 2023 • Yujiang Wang, Gabrielle M Schroeder, Jonathan J Horsley, Mariella Panagiotopoulou, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Peter N Taylor

To assess the localising value of band power abnormality, we computed DRS - a measure of how different the surgically resected and spared tissue were in terms of band power abnormalities - over time.

EEG