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Found 12 papers, 0 papers with code
Virtual Gram staining of label-free bacteria using darkfield microscopy and deep learning
Gram staining has been one of the most frequently used staining protocols in microbiology for over a century, utilized across various fields, including diagnostics, food safety, and environmental monitoring.
Virtual histological staining of unlabeled autopsy tissue
Histological examination is a crucial step in an autopsy; however, the traditional histochemical staining of post-mortem samples faces multiple challenges, including the inferior staining quality due to autolysis caused by delayed fixation of cadaver tissue, as well as the resource-intensive nature of chemical staining procedures covering large tissue areas, which demand substantial labor, cost, and time.
Virtual stain transfer in histology via cascaded deep neural networks
Unlike a single neural network structure which only takes one stain type as input to digitally output images of another stain type, C-DNN first uses virtual staining to transform autofluorescence microscopy images into H&E and then performs stain transfer from H&E to the domain of the other stain in a cascaded manner.
Virtual staining of defocused autofluorescence images of unlabeled tissue using deep neural networks
Here, we introduce a fast virtual staining framework that can stain defocused autofluorescence images of unlabeled tissue, achieving equivalent performance to virtual staining of in-focus label-free images, also saving significant imaging time by lowering the microscope's autofocusing precision.
Label-free virtual HER2 immunohistochemical staining of breast tissue using deep learning
The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation of pathogenesis.
Deep learning-based transformation of the H&E stain into special stains
Based on evaluation by three renal pathologists, followed by adjudication by a fourth renal pathologist, we show that the generation of virtual special stains from existing H&E images improves the diagnosis in several non-neoplastic kidney diseases sampled from 58 unique subjects.
Deep learning-based holographic polarization microscopy
Our analysis shows that a trained deep neural network can extract the birefringence information using both the sample specific morphological features as well as the holographic amplitude and phase distribution.
Digital synthesis of histological stains using micro-structured and multiplexed virtual staining of label-free tissue
This approach uses a single deep neural network that receives two different sources of information at its input: (1) autofluorescence images of the label-free tissue sample, and (2) a digital staining matrix which represents the desired microscopic map of different stains to be virtually generated at the same tissue section.
Deep learning-based color holographic microscopy
We report a framework based on a generative adversarial network (GAN) that performs high-fidelity color image reconstruction using a single hologram of a sample that is illuminated simultaneously by light at three different wavelengths.
Resolution enhancement in scanning electron microscopy using deep learning
We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network.
Cross-modality deep learning brings bright-field microscopy contrast to holography
Deep learning brings bright-field microscopy contrast to holographic images of a sample volume, bridging the volumetric imaging capability of holography with the speckle- and artifact-free image contrast of bright-field incoherent microscopy.
Deep learning-based super-resolution in coherent imaging systems
We present a deep learning framework based on a generative adversarial network (GAN) to perform super-resolution in coherent imaging systems.
