no code implementations • 22 Jul 2024 • Kshitij Ingale, Sun Hae Hong, Qiyuan Hu, Renyu Zhang, Bo Osinski, Mina Khoshdeli, Josh Och, Kunal Nagpal, Martin C. Stumpe, Rohan P. Joshi
In this work, models were trained for simultaneous prediction of multiple DNA alterations from H&E images using a multi-task approach.
no code implementations • 12 Oct 2023 • Qiyuan Hu, Abbas A. Rizvi, Geoffery Schau, Kshitij Ingale, Yoni Muller, Rachel Baits, Sebastian Pretzer, Aïcha BenTaieb, Abigail Gordhamer, Roberto Nussenzveig, Adam Cole, Matthew O. Leavitt, Rohan P. Joshi, Nike Beaubier, Martin C. Stumpe, Kunal Nagpal
As such, prediction of MSI status from hematoxylin and eosin (H&E) stained whole-slide images (WSIs) could identify prostate cancer patients most likely to benefit from confirmatory testing and becoming eligible for immunotherapy.
no code implementations • 11 Oct 2023 • Kshitij Ingale, Sun Hae Hong, Josh S. K. Bell, Abbas Rizvi, Amy Welch, Lingdao Sha, Irvin Ho, Kunal Nagpal, Aicha Bentaieb, Rohan P Joshi, Martin C Stumpe
MET protein overexpression is a targetable event in non-small cell lung cancer (NSCLC) and is the subject of active drug development.
no code implementations • 25 Nov 2020 • Ellery Wulczyn, Kunal Nagpal, Matthew Symonds, Melissa Moran, Markus Plass, Robert Reihs, Farah Nader, Fraser Tan, Yuannan Cai, Trissia Brown, Isabelle Flament-Auvigne, Mahul B. Amin, Martin C. Stumpe, Heimo Muller, Peter Regitnig, Andreas Holzinger, Greg S. Corrado, Lily H. Peng, Po-Hsuan Cameron Chen, David F. Steiner, Kurt Zatloukal, Yun Liu, Craig H. Mermel
's C-indices were 0. 87 and 0. 85 for continuous and discrete grading, respectively, compared to 0. 79 (95%CI 0. 71-0. 86) for GG obtained from the reports.
no code implementations • 21 Nov 2018 • Po-Hsuan Cameron Chen, Krishna Gadepalli, Robert MacDonald, Yun Liu, Kunal Nagpal, Timo Kohlberger, Jeffrey Dean, Greg S. Corrado, Jason D. Hipp, Martin C. Stumpe
We demonstrate the utility of ARM in the detection of lymph node metastases in breast cancer and the identification of prostate cancer with a latency that supports real-time workflows.
no code implementations • 15 Nov 2018 • Kunal Nagpal, Davis Foote, Yun Liu, Po-Hsuan, Chen, Ellery Wulczyn, Fraser Tan, Niels Olson, Jenny L. Smith, Arash Mohtashamian, James H. Wren, Greg S. Corrado, Robert MacDonald, Lily H. Peng, Mahul B. Amin, Andrew J. Evans, Ankur R. Sangoi, Craig H. Mermel, Jason D. Hipp, Martin C. Stumpe
For prostate cancer patients, the Gleason score is one of the most important prognostic factors, potentially determining treatment independent of the stage.