Search Results for author: Laura Manduchi

Found 15 papers, 9 papers with code

Leveraging Cardiovascular Simulations for In-Vivo Prediction of Cardiac Biomarkers

no code implementations23 Dec 2024 Laura Manduchi, Antoine Wehenkel, Jens Behrmann, Luca Pegolotti, Andy C. Miller, Ozan Sener, Marco Cuturi, Guillermo Sapiro, Jörn-Henrik Jacobsen

Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools for studying cardiovascular systems.

Hierarchical Clustering for Conditional Diffusion in Image Generation

1 code implementation22 Oct 2024 Jorge da Silva Goncalves, Laura Manduchi, Moritz Vandenhirtz, Julia E. Vogt

This paper addresses this gap by introducing TreeDiffusion, a deep generative model that conditions Diffusion Models on hierarchical clusters to obtain high-quality, cluster-specific generations.

Clustering Image Generation

Structured Generations: Using Hierarchical Clusters to guide Diffusion Models

1 code implementation8 Jul 2024 Jorge da Silva Goncalves, Laura Manduchi, Moritz Vandenhirtz, Julia E. Vogt

This paper introduces Diffuse-TreeVAE, a deep generative model that integrates hierarchical clustering into the framework of Denoising Diffusion Probabilistic Models (DDPMs).

Clustering Denoising

scTree: Discovering Cellular Hierarchies in the Presence of Batch Effects in scRNA-seq Data

1 code implementation27 Jun 2024 Moritz Vandenhirtz, Florian Barkmann, Laura Manduchi, Julia E. Vogt, Valentina Boeva

We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data.

Clustering

Simulation-based Inference for Cardiovascular Models

no code implementations26 Jul 2023 Antoine Wehenkel, Laura Manduchi, Jens Behrmann, Luca Pegolotti, Andrew C. Miller, Guillermo Sapiro, Ozan Sener, Marco Cuturi, Jörn-Henrik Jacobsen

Over the past decades, hemodynamics simulators have steadily evolved and have become tools of choice for studying cardiovascular systems in-silico.

parameter estimation

Signal Is Harder To Learn Than Bias: Debiasing with Focal Loss

1 code implementation31 May 2023 Moritz Vandenhirtz, Laura Manduchi, Ričards Marcinkevičs, Julia E. Vogt

We propose Signal is Harder (SiH), a variational-autoencoder-based method that simultaneously trains a biased and unbiased classifier using a novel, disentangling reweighting scheme inspired by the focal loss.

Decision Making Domain Generalization +1

Anomaly Detection in Echocardiograms with Dynamic Variational Trajectory Models

1 code implementation30 Jun 2022 Alain Ryser, Laura Manduchi, Fabian Laumer, Holger Michel, Sven Wellmann, Julia E. Vogt

The introduced method takes advantage of the periodic nature of the heart cycle to learn three variants of a variational latent trajectory model (TVAE).

Anomaly Detection

Learning Group Importance using the Differentiable Hypergeometric Distribution

1 code implementation3 Mar 2022 Thomas M. Sutter, Laura Manduchi, Alain Ryser, Julia E. Vogt

We introduce reparameterizable gradients to learn the importance between groups and highlight the advantage of explicitly learning the size of subsets in two typical applications: weakly-supervised learning and clustering.

Clustering Selection bias +1

Deep Conditional Gaussian Mixture Model for Constrained Clustering

1 code implementation NeurIPS 2021 Laura Manduchi, Kieran Chin-Cheong, Holger Michel, Sven Wellmann, Julia E. Vogt

Constrained clustering has gained significant attention in the field of machine learning as it can leverage prior information on a growing amount of only partially labeled data.

Constrained Clustering model +1

A Probabilistic Approach to Constrained Deep Clustering

no code implementations1 Jan 2021 Laura Manduchi, Kieran Chin-Cheong, Holger Michel, Sven Wellmann, Julia E Vogt

Clustering with constraints has gained significant attention in the field of semi-supervised machine learning as it can leverage partial prior information on a growing amount of unlabelled data.

Constrained Clustering Deep Clustering +1

DPSOM: Deep Probabilistic Clustering with Self-Organizing Maps

2 code implementations3 Oct 2019 Laura Manduchi, Matthias Hüser, Julia Vogt, Gunnar Rätsch, Vincent Fortuin

We show that DPSOM achieves superior clustering performance compared to current deep clustering methods on MNIST/Fashion-MNIST, while maintaining the favourable visualization properties of SOMs.

Clustering Deep Clustering +4

Variational pSOM: Deep Probabilistic Clustering with Self-Organizing Maps

no code implementations25 Sep 2019 Laura Manduchi, Matthias Hüser, Gunnar Rätsch, Vincent Fortuin

There are very performant deep clustering models on the one hand and interpretable representation learning techniques, often relying on latent topological structures such as self-organizing maps, on the other hand.

Clustering Deep Clustering +3

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