no code implementations • 2 Mar 2023 • Bo Zhou, Yingda Xia, Jiawen Yao, Le Lu, Jingren Zhou, Chi Liu, James S. Duncan, Ling Zhang
Accurate detection, segmentation, and differential diagnosis of the full taxonomy of pancreatic lesions, i. e., normal, seven major types of lesions, and other lesions, is critical to aid the clinical decision-making of patient management and treatment.
no code implementations • 11 Feb 2023 • Yankai Jiang, Mingze Sun, Heng Guo, Ke Yan, Le Lu, Minfeng Xu
Self-supervised learning (SSL) has recently achieved promising performance for 3D medical image segmentation tasks.
no code implementations • 1 Feb 2023 • Zhanghexuan Ji, Dazhou Guo, Puyang Wang, Ke Yan, Le Lu, Minfeng Xu, Jingren Zhou, Qifeng Wang, Jia Ge, Mingchen Gao, Xianghua Ye, Dakai Jin
Deep learning empowers the mainstream medical image segmentation methods.
no code implementations • 28 Jan 2023 • Jieneng Chen, Yingda Xia, Jiawen Yao, Ke Yan, Jianpeng Zhang, Le Lu, Fakai Wang, Bo Zhou, Mingyan Qiu, Qihang Yu, Mingze Yuan, Wei Fang, Yuxing Tang, Minfeng Xu, Jian Zhou, Yuqian Zhao, Qifeng Wang, Xianghua Ye, Xiaoli Yin, Yu Shi, Xin Chen, Jingren Zhou, Alan Yuille, Zaiyi Liu, Ling Zhang
A certain number of AI models need to be assembled non-trivially to match the diagnostic process of a human reading a CT scan.
no code implementations • 4 Jan 2023 • Zhilin Zheng, Xu Fang, Jiawen Yao, Mengmeng Zhu, Le Lu, Lingyun Huang, Jing Xiao, Yu Shi, Hong Lu, Jianping Lu, Ling Zhang, Chengwei Shao, Yun Bian
Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors.
1 code implementation • 5 Dec 2022 • Heng Guo, Jianfeng Zhang, Ke Yan, Le Lu, Minfeng Xu
For rib parsing, CT scans have been annotated at the rib instance-level for quantitative evaluation, similarly for spine vertebrae and abdominal organs.
no code implementations • 2 Aug 2022 • Minfeng Xu, Heng Guo, Jianfeng Zhang, Ke Yan, Le Lu
Accurate and robust abdominal multi-organ segmentation from CT imaging of different modalities is a challenging task due to complex inter- and intra-organ shape and appearance variations among abdominal organs.
1 code implementation • 29 Jun 2022 • Zihan Li, Yunxiang Li, Qingde Li, Puyang Wang, You Zhang, Dazhou Guo, Le Lu, Dakai Jin, Qingqi Hong
In our model, medical text annotation is introduced to compensate for the quality deficiency in image data.
Ranked #1 on
Medical Image Segmentation
on MoNuSeg
1 code implementation • CVPR 2022 • Wei Zhu, Le Lu, Jing Xiao, Mei Han, Jiebo Luo, Adam P. Harrison
Adversarial domain generalization is a popular approach to DG, but conventional approaches (1) struggle to sufficiently align features so that local neighborhoods are mixed across domains; and (2) can suffer from feature space over collapse which can threaten generalization performance.
no code implementations • 5 Jan 2022 • Fakai Wang, Kang Zheng, Le Lu, Jing Xiao, Min Wu, Chang-Fu Kuo, Shun Miao
Osteoporosis is a common chronic metabolic bone disease often under-diagnosed and under-treated due to the limited access to bone mineral density (BMD) examinations, e. g. via Dual-energy X-ray Absorptiometry (DXA).
no code implementations • 16 Dec 2021 • Kang Zheng, Yirui Wang, Chen-I Hsieh, Le Lu, Jing Xiao, Chang-Fu Kuo, Shun Miao
In this work, we propose a computer-aided diagnosis approach to provide more accurate and consistent assessments of both composite and fine-grained OA grades simultaneously.
no code implementations • 1 Nov 2021 • Dazhou Guo, Jia Ge, Xianghua Ye, Senxiang Yan, Yi Xin, Yuchen Song, Bing-shen Huang, Tsung-Min Hung, Zhuotun Zhu, Ling Peng, Yanping Ren, Rui Liu, Gong Zhang, Mengyuan Mao, Xiaohua Chen, Zhongjie Lu, Wenxiang Li, Yuzhen Chen, Lingyun Huang, Jing Xiao, Adam P. Harrison, Le Lu, Chien-Yu Lin, Dakai Jin, Tsung-Ying Ho
Accurate organ at risk (OAR) segmentation is critical to reduce the radiotherapy post-treatment complications.
1 code implementation • 22 Oct 2021 • Ethan H. Nguyen, Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo
Compared with the conventional bounding box representation, the proposed bounding circle representation innovates in three-fold: (1) it is optimized for ball-shaped biomedical objects; (2) The circle representation reduced the degree of freedom compared with box representation; (3) It is naturally more rotation invariant.
Ranked #1 on
Medical Object Detection
on MoNuSeg 2018
no code implementations • 17 Oct 2021 • Peng Wang, YuHsuan Wu, Bolin Lai, Xiao-Yun Zhou, Le Lu, Wendi Liu, Huabang Zhou, Lingyun Huang, Jing Xiao, Adam P. Harrison, Ningyang Jia, Heping Hu
Results: the proposed CAD solution achieves a mean F1 score of 0. 62, outperforming the abdominal radiologist (0. 47), matching the junior hepatology radiologist (0. 61), and underperforming the senior hepatology radiologist (0. 68).
no code implementations • 12 Oct 2021 • Bowen Li, Dar-In Tai, Ke Yan, Yi-Cheng Chen, Shiu-Feng Huang, Tse-Hwa Hsu, Wan-Ting Yu, Jing Xiao, Le Lu, Adam P. Harrison
High diagnostic performance was observed across all viewpoints: area under the curves of the ROC to classify >=mild, >=moderate, =severe steatosis grades were 0. 85, 0. 90, and 0. 93, respectively.
no code implementations • 11 Oct 2021 • Xianghua Ye, Dazhou Guo, Chen-Kan Tseng, Jia Ge, Tsung-Min Hung, Ping-Ching Pai, Yanping Ren, Lu Zheng, Xinli Zhu, Ling Peng, Ying Chen, Xiaohua Chen, Chen-Yu Chou, Danni Chen, Jiaze Yu, Yuzhen Chen, Feiran Jiao, Yi Xin, Lingyun Huang, Guotong Xie, Jing Xiao, Le Lu, Senxiang Yan, Dakai Jin, Tsung-Ying Ho
252 institution-1 patients had a treatment planning-CT (pCT) and a pair of diagnostic FDG-PETCT; 354 patients from other 3 institutions had only pCT.
no code implementations • 23 Sep 2021 • Fengze Liu, Ke Yan, Adam Harrison, Dazhou Guo, Le Lu, Alan Yuille, Lingyun Huang, Guotong Xie, Jing Xiao, Xianghua Ye, Dakai Jin
In this work, we introduce a fast and accurate method for unsupervised 3D medical image registration.
no code implementations • 20 Sep 2021 • Dazhou Guo, Xianghua Ye, Jia Ge, Xing Di, Le Lu, Lingyun Huang, Guotong Xie, Jing Xiao, Zhongjie Liu, Ling Peng, Senxiang Yan, Dakai Jin
Lymph node station (LNS) delineation from computed tomography (CT) scans is an indispensable step in radiation oncology workflow.
no code implementations • 17 Aug 2021 • Chi-Tung Cheng, Jinzheng Cai, Wei Teng, Youjing Zheng, YuTing Huang, Yu-Chao Wang, Chien-Wei Peng, YouBao Tang, Wei-Chen Lee, Ta-Sen Yeh, Jing Xiao, Le Lu, Chien-Hung Liao, Adam P. Harrison
We develop a flexible three-dimensional deep algorithm, called hetero-phase volumetric detection (HPVD), that can accept any combination of contrast-phase inputs and with adjustable sensitivity depending on the clinical purpose.
no code implementations • 5 May 2021 • YouBao Tang, Ke Yan, Jinzheng Cai, Lingyun Huang, Guotong Xie, Jing Xiao, JingJing Lu, Gigin Lin, Le Lu
PDNet learns comprehensive and representative deep image features for our tasks and produces more accurate results on both lesion segmentation and RECIST diameter prediction.
no code implementations • 3 May 2021 • YouBao Tang, Jinzheng Cai, Ke Yan, Lingyun Huang, Guotong Xie, Jing Xiao, JingJing Lu, Gigin Lin, Le Lu
Accurately segmenting a variety of clinically significant lesions from whole body computed tomography (CT) scans is a critical task on precision oncology imaging, denoted as universal lesion segmentation (ULS).
no code implementations • 29 Apr 2021 • Xiao-Yun Zhou, Bolin Lai, Weijian Li, Yirui Wang, Kang Zheng, Fakai Wang, ChiHung Lin, Le Lu, Lingyun Huang, Mei Han, Guotong Xie, Jing Xiao, Kuo Chang-Fu, Adam Harrison, Shun Miao
It first trains a DAG model on the labeled data and then fine-tunes the pre-trained model on the unlabeled data with a teacher-student SSL mechanism.
no code implementations • 12 Apr 2021 • Bowen Li, Xinping Ren, Ke Yan, Le Lu, Lingyun Huang, Guotong Xie, Jing Xiao, Dar-In Tai, Adam P. Harrison
Importantly, ADDLE does not expect multiple raters per image in training, meaning it can readily learn from data mined from hospital archives.
1 code implementation • 7 Apr 2021 • Ashwin Raju, Shun Miao, Dakai Jin, Le Lu, Junzhou Huang, Adam P. Harrison
DISSMs use a deep implicit surface representation to produce a compact and descriptive shape latent space that permits statistical models of anatomical variance.
no code implementations • 5 Apr 2021 • Fakai Wang, Kang Zheng, Yirui Wang, XiaoYun Zhou, Le Lu, Jing Xiao, Min Wu, Chang-Fu Kuo, Shun Miao
In this paper, we propose a method to predict BMD from Chest X-ray (CXR), one of the most common, accessible, and low-cost medical image examinations.
no code implementations • 24 Mar 2021 • Kang Zheng, Yirui Wang, XiaoYun Zhou, Fakai Wang, Le Lu, ChiHung Lin, Lingyun Huang, Guotong Xie, Jing Xiao, Chang-Fu Kuo, Shun Miao
Specifically, we propose a new semi-supervised self-training algorithm to train the BMD regression model using images coupled with DEXA measured BMDs and unlabeled images with pseudo BMDs.
no code implementations • 24 Mar 2021 • Bolin Lai, YuHsuan Wu, Xiao-Yun Zhou, Peng Wang, Le Lu, Lingyun Huang, Mei Han, Jing Xiao, Heping Hu, Adam P. Harrison
Lesion detection serves a critical role in early diagnosis and has been well explored in recent years due to methodological advancesand increased data availability.
no code implementations • 9 Mar 2021 • Jieneng Chen, Ke Yan, Yu-Dong Zhang, YouBao Tang, Xun Xu, Shuwen Sun, Qiuping Liu, Lingyun Huang, Jing Xiao, Alan L. Yuille, Ya zhang, Le Lu
(2) The sampled deep vertex features with positional embedding are mapped into a sequential space and decoded by a multilayer perceptron (MLP) for semantic classification.
14 code implementations • 8 Feb 2021 • Jieneng Chen, Yongyi Lu, Qihang Yu, Xiangde Luo, Ehsan Adeli, Yan Wang, Le Lu, Alan L. Yuille, Yuyin Zhou
Medical image segmentation is an essential prerequisite for developing healthcare systems, especially for disease diagnosis and treatment planning.
Ranked #3 on
Medical Image Segmentation
on ACDC
no code implementations • 30 Dec 2020 • Yirui Wang, Kang Zheng, Chi-Tung Chang, Xiao-Yun Zhou, Zhilin Zheng, Lingyun Huang, Jing Xiao, Le Lu, Chien-Hung Liao, Shun Miao
Exploiting available medical records to train high performance computer-aided diagnosis (CAD) models via the semi-supervised learning (SSL) setting is emerging to tackle the prohibitively high labor costs involved in large-scale medical image annotations.
no code implementations • CVPR 2021 • Fakai Wang, Kang Zheng, Le Lu, Jing Xiao, Min Wu, Shun Miao
This paper proposes a robust and accurate method that effectively exploits the anatomical knowledge of the spine to facilitate vertebra localization and identification.
no code implementations • 13 Dec 2020 • Bolin Lai, YuHsuan Wu, Xiaoyu Bai, Xiao-Yun Zhou, Peng Wang, Jinzheng Cai, Yuankai Huo, Lingyun Huang, Yong Xia, Jing Xiao, Le Lu, Heping Hu, Adam Harrison
Using radiological scans to identify liver tumors is crucial for proper patient treatment.
no code implementations • 12 Dec 2020 • Chun-Hung Chao, Hsien-Tzu Cheng, Tsung-Ying Ho, Le Lu, Min Sun
The proposed method is evaluated on two published radiotherapy target contouring datasets of nasopharyngeal and esophageal cancer.
1 code implementation • CVPR 2021 • Jinzheng Cai, YouBao Tang, Ke Yan, Adam P. Harrison, Jing Xiao, Gigin Lin, Le Lu
In this work, we present deep lesion tracker (DLT), a deep learning approach that uses both appearance- and anatomical-based signals.
no code implementations • CVPR 2021 • Tianyi Zhao, Kai Cao, Jiawen Yao, Isabella Nogues, Le Lu, Lingyun Huang, Jing Xiao, Zhaozheng Yin, Ling Zhang
We exploit the feasibility to distinguish pancreatic ductal adenocarcinoma (PDAC) from the nine other nonPDAC masses using multi-phase CT imaging.
no code implementations • 7 Dec 2020 • Xinyu Zhang, Yirui Wang, Chi-Tung Cheng, Le Lu, Adam P. Harrison, Jing Xiao, Chien-Hung Liao, Shun Miao
Object detection methods are widely adopted for computer-aided diagnosis using medical images.
no code implementations • 4 Dec 2020 • Ke Yan, Jinzheng Cai, Dakai Jin, Shun Miao, Dazhou Guo, Adam P. Harrison, YouBao Tang, Jing Xiao, JingJing Lu, Le Lu
We introduce such an approach, called Self-supervised Anatomical eMbedding (SAM).
1 code implementation • 2 Dec 2020 • Yuhang Lu, Kang Zheng, Weijian Li, Yirui Wang, Adam P. Harrison, ChiHung Lin, Song Wang, Jing Xiao, Le Lu, Chang-Fu Kuo, Shun Miao
In this work, we present Contour Transformer Network (CTN), a one-shot anatomy segmentation method with a naturally built-in human-in-the-loop mechanism.
1 code implementation • 5 Sep 2020 • Ke Yan, Jinzheng Cai, Youjing Zheng, Adam P. Harrison, Dakai Jin, YouBao Tang, Yuxing Tang, Lingyun Huang, Jing Xiao, Le Lu
For example, DeepLesion is such a large-scale CT image dataset with lesions of various types, but it also has many unlabeled lesions (missing annotations).
no code implementations • 5 Sep 2020 • Ashwin Raju, Zhanghexuan Ji, Chi Tung Cheng, Jinzheng Cai, Junzhou Huang, Jing Xiao, Le Lu, Chien-Hung Liao, Adam P. Harrison
Mask-based annotation of medical images, especially for 3D data, is a bottleneck in developing reliable machine learning models.
no code implementations • 30 Aug 2020 • Jinzheng Cai, Ke Yan, Chi-Tung Cheng, Jing Xiao, Chien-Hung Liao, Le Lu, Adam P. Harrison
Identifying, measuring and reporting lesions accurately and comprehensively from patient CT scans are important yet time-consuming procedures for physicians.
no code implementations • 29 Aug 2020 • Chun-Hung Chao, Zhuotun Zhu, Dazhou Guo, Ke Yan, Tsung-Ying Ho, Jinzheng Cai, Adam P. Harrison, Xianghua Ye, Jing Xiao, Alan Yuille, Min Sun, Le Lu, Dakai Jin
Specifically, we first utilize a 3D convolutional neural network with ROI-pooling to extract the GTV$_{LN}$'s instance-wise appearance features.
no code implementations • 27 Aug 2020 • Zhuotun Zhu, Dakai Jin, Ke Yan, Tsung-Ying Ho, Xianghua Ye, Dazhou Guo, Chun-Hung Chao, Jing Xiao, Alan Yuille, Le Lu
Finding, identifying and segmenting suspicious cancer metastasized lymph nodes from 3D multi-modality imaging is a clinical task of paramount importance.
no code implementations • 26 Aug 2020 • Jiawen Yao, Yu Shi, Le Lu, Jing Xiao, Ling Zhang
We present a multi-task CNN to accomplish both tasks of outcome and margin prediction where the network benefits from learning the tumor resection margin related features to improve survival prediction.
no code implementations • 24 Aug 2020 • Ling Zhang, Yu Shi, Jiawen Yao, Yun Bian, Kai Cao, Dakai Jin, Jing Xiao, Le Lu
A student model is trained on both manual and pseudo annotated multi-phase images.
no code implementations • 7 Aug 2020 • Bowen Li, Ke Yan, Dar-In Tai, Yuankai Huo, Le Lu, Jing Xiao, Adam P. Harrison
Ultrasound (US) is a critical modality for diagnosing liver fibrosis.
1 code implementation • 28 Jul 2020 • Mengyang Zhao, Aadarsh Jha, Quan Liu, Bryan A. Millis, Anita Mahadevan-Jansen, Le Lu, Bennett A. Landman, Matthew J. Tyskac, Yuankai Huo
With both embedding simulation and empirical validation via the four cohorts from the ISBI cell tracking challenge, the proposed Faster Mean-shift algorithm achieved 7-10 times speedup compared to the state-of-the-art embedding based cell instance segmentation and tracking algorithm.
no code implementations • 6 Jul 2020 • Yuhang Lu, Weijian Li, Kang Zheng, Yirui Wang, Adam P. Harrison, Chi-Hung Lin, Song Wang, Jing Xiao, Le Lu, Chang-Fu Kuo, Shun Miao
Accurate segmentation of critical anatomical structures is at the core of medical image analysis.
no code implementations • ECCV 2020 • Haomin Chen, Yirui Wang, Kang Zheng, Weijian Li, Chi-Tung Cheng, Adam P. Harrison, Jing Xiao, Gregory D. Hager, Le Lu, Chien-Hung Liao, Shun Miao
A new contrastive feature learning component in our Siamese network is designed to optimize the deep image features being more salient corresponding to the underlying semantic asymmetries (caused by pelvic fracture occurrences).
no code implementations • 28 Jun 2020 • Yuankai Huo, Jinzheng Cai, Chi-Tung Cheng, Ashwin Raju, Ke Yan, Bennett A. Landman, Jing Xiao, Le Lu, Chien-Hung Liao, Adam P. Harrison
To this end, we propose a fully-automated and multi-stage liver tumor characterization framework designed for dynamic contrast computed tomography (CT).
1 code implementation • 3 Jun 2020 • Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Ye Chen, Joseph T. Roland, Le Lu, Bennett A. Landman, Agnes B. Fogo, Yuankai Huo
In this work, we propose CircleNet, a simple anchor-free detection method with circle representation for detection of the ball-shaped glomerulus.
no code implementations • 28 May 2020 • Ke Yan, Jinzheng Cai, Adam P. Harrison, Dakai Jin, Jing Xiao, Le Lu
First, we learn a multi-head multi-task lesion detector using all datasets and generate lesion proposals on DeepLesion.
Ranked #5 on
Medical Object Detection
on DeepLesion
(using extra training data)
no code implementations • ECCV 2020 • Ashwin Raju, Chi-Tung Cheng, Yunakai Huo, Jinzheng Cai, Junzhou Huang, Jing Xiao, Le Lu, ChienHuang Liao, Adam P. Harrison
In medical imaging, organ/pathology segmentation models trained on current publicly available and fully-annotated datasets usually do not well-represent the heterogeneous modalities, phases, pathologies, and clinical scenarios encountered in real environments.
no code implementations • 27 May 2020 • Zhuotun Zhu, Ke Yan, Dakai Jin, Jinzheng Cai, Tsung-Ying Ho, Adam P. Harrison, Dazhou Guo, Chun-Hung Chao, Xianghua Ye, Jing Xiao, Alan Yuille, Le Lu
We focus on the detection and segmentation of oncology-significant (or suspicious cancer metastasized) lymph nodes (OSLNs), which has not been studied before as a computational task.
no code implementations • ECCV 2020 • Fengze Liu, Jingzheng Cai, Yuankai Huo, Chi-Tung Cheng, Ashwin Raju, Dakai Jin, Jing Xiao, Alan Yuille, Le Lu, Chien-Hung Liao, Adam P. Harrison
We extensively evaluate our JSSR system on a large-scale medical image dataset containing 1, 485 patient CT imaging studies of four different phases (i. e., 5, 940 3D CT scans with pathological livers) on the registration, segmentation and synthesis tasks.
1 code implementation • ECCV 2020 • Weijian Li, Yuhang Lu, Kang Zheng, Haofu Liao, Chi-Hung Lin, Jiebo Luo, Chi-Tung Cheng, Jing Xiao, Le Lu, Chang-Fu Kuo, Shun Miao
Image landmark detection aims to automatically identify the locations of predefined fiducial points.
Ranked #4 on
Face Alignment
on COFW-68
no code implementations • CVPR 2020 • Dazhou Guo, Dakai Jin, Zhuotun Zhu, Tsung-Ying Ho, Adam P. Harrison, Chun-Hung Chao, Jing Xiao, Alan Yuille, Chien-Yu Lin, Le Lu
This is the goal of our work, where we introduce stratified organ at risk segmentation (SOARS), an approach that stratifies OARs into anchor, mid-level, and small & hard (S&H) categories.
1 code implementation • 16 Apr 2020 • Weijian Li, Haofu Liao, Shun Miao, Le Lu, Jiebo Luo
To recover from the transformed images back to the original subject, the landmark detector is forced to learn spatial locations that contain the consistent semantic meanings both for the paired intra-subject images and between the paired inter-subject images.
1 code implementation • 21 Jan 2020 • Jinzheng Cai, Adam P. Harrison, Youjing Zheng, Ke Yan, Yuankai Huo, Jing Xiao, Lin Yang, Le Lu
This is the goal of our work, where we develop a powerful system to harvest missing lesions from the DeepLesion dataset at high precision.
no code implementations • 5 Sep 2019 • Bo Zhou, Adam P. Harrison, Jiawen Yao, Chi-Tung Cheng, Jing Xiao, Chien-Hung Liao, Le Lu
This is the focus of our work, where we present a principled data curation tool to extract multi-phase CT liver studies and identify each scan's phase from a real-world and heterogenous hospital PACS dataset.
no code implementations • 4 Sep 2019 • Dakai Jin, Dazhou Guo, Tsung-Ying Ho, Adam P. Harrison, Jing Xiao, Chen-Kan Tseng, Le Lu
Gross tumor volume (GTV) segmentation is a critical step in esophageal cancer radiotherapy treatment planning.
no code implementations • 4 Sep 2019 • Dakai Jin, Dazhou Guo, Tsung-Ying Ho, Adam P. Harrison, Jing Xiao, Chen-Kan Tseng, Le Lu
Clinical target volume (CTV) delineation from radiotherapy computed tomography (RTCT) images is used to define the treatment areas containing the gross tumor volume (GTV) and/or sub-clinical malignant disease for radiotherapy (RT).
no code implementations • 4 Sep 2019 • Yirui Wang, Le Lu, Chi-Tung Cheng, Dakai Jin, Adam P. Harrison, Jing Xiao, Chien-Hung Liao, Shun Miao
In this paper, we propose a two-stage hip and pelvic fracture detection method that executes localized fracture classification using weakly supervised ROI mining.
no code implementations • 5 Apr 2019 • Chun-Hung Chao, Yen-Chi Cheng, Hsien-Tzu Cheng, Chi-Wen Huang, Tsung-Ying Ho, Chen-Kan Tseng, Le Lu, Min Sun
Instead, inspired by the treating methodology of considering meaningful information across slices, we used Gated Graph Neural Network to frame this problem more efficiently.
no code implementations • 23 Feb 2019 • Ling Zhang, Le Lu, Xiaosong Wang, Robert M. Zhu, Mohammadhadi Bagheri, Ronald M. Summers, Jianhua Yao
Results validate that the ST-ConvLSTM produces a Dice score of 83. 2%+-5. 1% and a RVD of 11. 2%+-10. 8%, both significantly outperforming (p<0. 05) other compared methods of linear model, ConvLSTM, and generative adversarial network (GAN) under the metric of predicting future tumor volumes.
no code implementations • 19 Jul 2018 • Yu-Xing Tang, Xiaosong Wang, Adam P. Harrison, Le Lu, Jing Xiao, Ronald M. Summers
In addition, highly confident samples (measured by classification probabilities) and their corresponding class-conditional heatmaps (generated by the CNN) are extracted and further fed into the AGCL framework to guide the learning of more distinctive convolutional features in the next iteration.
no code implementations • 18 Jul 2018 • Youbao Tang, Jinzheng Cai, Le Lu, Adam P. Harrison, Ke Yan, Jing Xiao, Lin Yang, Ronald M. Summers
The first GAN reduces the noise in the CT image and the second GAN generates a higher resolution image with enhanced boundaries and high contrast.
no code implementations • 3 Jul 2018 • Jinzheng Cai, Le Lu, Adam P. Harrison, Xiaoshuang Shi, Pingjun Chen, Lin Yang
Given image labels as the only supervisory signal, we focus on harvesting, or mining, thoracic disease localizations from chest X-ray images.
no code implementations • 2 Jul 2018 • Jinzheng Cai, You-Bao Tang, Le Lu, Adam P. Harrison, Ke Yan, Jing Xiao, Lin Yang, Ronald M. Summers
Volumetric lesion segmentation from computed tomography (CT) images is a powerful means to precisely assess multiple time-point lesion/tumor changes.
no code implementations • 30 Mar 2018 • Jinzheng Cai, Le Lu, Fuyong Xing, Lin Yang
Automatic pancreas segmentation in radiology images, eg., computed tomography (CT) and magnetic resonance imaging (MRI), is frequently required by computer-aided screening, diagnosis, and quantitative assessment.
no code implementations • 25 Jan 2018 • Zhihui Guo, Ling Zhang, Le Lu, Mohammadhadi Bagheri, Ronald M. Summers, Milan Sonka, Jianhua Yao
The cost for each node of the graph is determined by the UNet probability maps.
no code implementations • 25 Jan 2018 • Ling Zhang, Le Lu, Ronald M. Summers, Electron Kebebew, Jianhua Yao
Tumor growth is associated with cell invasion and mass-effect, which are traditionally formulated by mathematical models, namely reaction-diffusion equations and biomechanics.
no code implementations • 25 Jan 2018 • Ling Zhang, Vissagan Gopalakrishnan, Le Lu, Ronald M. Summers, Joel Moss, Jianhua Yao
In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.
no code implementations • 25 Jan 2018 • Jinzheng Cai, You-Bao Tang, Le Lu, Adam P. Harrison, Ke Yan, Jing Xiao, Lin Yang, Ronald M. Summers
Toward this end, we introduce a convolutional neural network based weakly supervised self-paced segmentation (WSSS) method to 1) generate the initial lesion segmentation on the axial RECIST-slice; 2) learn the data distribution on RECIST-slices; 3) adapt to segment the whole volume slice by slice to finally obtain a volumetric segmentation.
no code implementations • 25 Jan 2018 • Ling Zhang, Le Lu, Isabella Nogues, Ronald M. Summers, Shaoxiong Liu, Jianhua Yao
However, the success of most traditional classification methods relies on the presence of accurate cell segmentations.
no code implementations • CVPR 2018 • Xiaosong Wang, Yifan Peng, Le Lu, Zhiyong Lu, Ronald M. Summers
Chest X-rays are one of the most common radiological examinations in daily clinical routines.
1 code implementation • 16 Dec 2017 • Yifan Peng, Xiaosong Wang, Le Lu, Mohammadhadi Bagheri, Ronald Summers, Zhiyong Lu
Negative and uncertain medical findings are frequent in radiology reports, but discriminating them from positive findings remains challenging for information extraction.
no code implementations • CVPR 2018 • Ke Yan, Xiaosong Wang, Le Lu, Ling Zhang, Adam Harrison, Mohammadhad Bagheri, Ronald Summers
Then, a triplet network is utilized to learn lesion embeddings with a sequential sampling strategy to depict their hierarchical similarity structure.
1 code implementation • 4 Oct 2017 • Ke Yan, Xiaosong Wang, Le Lu, Ronald M. Summers
We categorize the collection of lesions using an unsupervised deep mining scheme to generate clustered pseudo lesion labels.
no code implementations • 16 Jul 2017 • Jinzheng Cai, Le Lu, Yuanpu Xie, Fuyong Xing, Lin Yang
The output layer of this network module is then connected to recurrent layers and can be fine-tuned for contextual learning, in an end-to-end manner.
2 code implementations • 12 Jul 2017 • Ke Yan, Le Lu, Ronald M. Summers
In this paper, we propose a convolutional neural network (CNN) based Unsupervised Body part Regression (UBR) algorithm to address this problem.
no code implementations • 12 Jun 2017 • Adam P. Harrison, Ziyue Xu, Kevin George, Le Lu, Ronald M. Summers, Daniel J. Mollura
Pathological lung segmentation (PLS) is an important, yet challenging, medical image application due to the wide variability of pathological lung appearance and shape.
no code implementations • 1 Jun 2017 • Ling Zhang, Le Lu, Ronald M. Summers, Electron Kebebew, Jianhua Yao
Our predictive model is pretrained on a group data set and personalized on the target patient data to estimate the future spatio-temporal progression of the patient's tumor.
23 code implementations • CVPR 2017 • Xiaosong Wang, Yifan Peng, Le Lu, Zhiyong Lu, Mohammadhadi Bagheri, Ronald M. Summers
The chest X-ray is one of the most commonly accessible radiological examinations for screening and diagnosis of many lung diseases.
no code implementations • 31 Jan 2017 • Holger R. Roth, Le Lu, Nathan Lay, Adam P. Harrison, Amal Farag, Andrew Sohn, Ronald M. Summers
Accurate and automatic organ segmentation from 3D radiological scans is an important yet challenging problem for medical image analysis.
Ranked #1 on
3D Medical Imaging Segmentation
on TCIA Pancreas-CT
no code implementations • 23 Jan 2017 • Xiaosong Wang, Le Lu, Hoo-chang Shin, Lauren Kim, Mohammadhadi Bagheri, Isabella Nogues, Jianhua Yao, Ronald M. Summers
The recent rapid and tremendous success of deep convolutional neural networks (CNN) on many challenging computer vision tasks largely derives from the accessibility of the well-annotated ImageNet and PASCAL VOC datasets.
no code implementations • 19 Jan 2017 • Mingchen Gao, Ziyue Xu, Le Lu, Adam P. Harrison, Ronald M. Summers, Daniel J. Mollura
Accurately predicting and detecting interstitial lung disease (ILD) patterns given any computed tomography (CT) slice without any pre-processing prerequisites, such as manually delineated regions of interest (ROIs), is a clinically desirable, yet challenging goal.
no code implementations • 24 Jun 2016 • Holger R. Roth, Le Lu, Amal Farag, Andrew Sohn, Ronald M. Summers
Accurate automatic organ segmentation is an important yet challenging problem for medical image analysis.
1 code implementation • CVPR 2016 • Hoo-chang Shin, Kirk Roberts, Le Lu, Dina Demner-Fushman, Jianhua Yao, Ronald M. Summers
Recurrent neural networks (RNNs) are then trained to describe the contexts of a detected disease, based on the deep CNN features.
no code implementations • 25 Mar 2016 • Xiaosong Wang, Le Lu, Hoo-chang Shin, Lauren Kim, Isabella Nogues, Jianhua Yao, Ronald Summers
Obtaining semantic labels on a large scale radiology image database (215, 786 key images from 61, 845 unique patients) is a prerequisite yet bottleneck to train highly effective deep convolutional neural network (CNN) models for image recognition.
no code implementations • 10 Feb 2016 • Hoo-chang Shin, Holger R. Roth, Mingchen Gao, Le Lu, Ziyue Xu, Isabella Nogues, Jianhua Yao, Daniel Mollura, Ronald M. Summers
Another effective method is transfer learning, i. e., fine-tuning CNN models pre-trained from natural image dataset to medical image tasks.
no code implementations • 29 Jan 2016 • Holger R. Roth, Yinong Wang, Jianhua Yao, Le Lu, Joseph E. Burns, Ronald M. Summers
In this work, we apply deep convolutional networks (ConvNets) for the automated detection of posterior element fractures of the spine.
no code implementations • 22 Jun 2015 • Holger R. Roth, Le Lu, Amal Farag, Hoo-chang Shin, Jiamin Liu, Evrim Turkbey, Ronald M. Summers
We propose and evaluate several variations of deep ConvNets in the context of hierarchical, coarse-to-fine classification on image patches and regions, i. e. superpixels.
no code implementations • CVPR 2015 • Hoo-chang Shin, Le Lu, Lauren Kim, Ari Seff, Jianhua Yao, Ronald M. Summers
We present an interleaved text/image deep learning system to extract and mine the semantic interactions of radiology images and reports from a national research hospital's picture archiving and communication system.
no code implementations • 22 May 2015 • Amal Farag, Le Lu, Holger R. Roth, Jiamin Liu, Evrim Turkbey, Ronald M. Summers
We present a bottom-up approach for pancreas segmentation in abdominal CT scans that is based on a hierarchy of information propagation by classifying image patches at different resolutions; and cascading superpixels.
no code implementations • 12 May 2015 • Holger R. Roth, Le Lu, Jiamin Liu, Jianhua Yao, Ari Seff, Kevin Cherry, Lauren Kim, Ronald M. Summers
By leveraging existing CAD systems, coordinates of regions or volumes of interest (ROI or VOI) for lesion candidates are generated in this step and function as input for a second tier, which is our focus in this study.
no code implementations • 4 May 2015 • Hoo-chang Shin, Le Lu, Lauren Kim, Ari Seff, Jianhua Yao, Ronald M. Summers
We present an interleaved text/image deep learning system to extract and mine the semantic interactions of radiology images and reports from a national research hospital's Picture Archiving and Communication System.
1 code implementation • 15 Apr 2015 • Holger R. Roth, Christopher T. Lee, Hoo-chang Shin, Ari Seff, Lauren Kim, Jianhua Yao, Le Lu, Ronald M. Summers
We show that a data augmentation approach can help to enrich the data set and improve classification performance.
no code implementations • 15 Apr 2015 • Holger R. Roth, Amal Farag, Le Lu, Evrim B. Turkbey, Ronald M. Summers
We evaluate our method on CT images of 82 patients (60 for training, 2 for validation, and 20 for testing).
no code implementations • 14 Aug 2014 • Ari Seff, Le Lu, Kevin M. Cherry, Holger Roth, Jiamin Liu, Shijun Wang, Joanne Hoffman, Evrim B. Turkbey, Ronald M. Summers
In this paper, we propose a new algorithm representation of decomposing the LN detection problem into a set of 2D object detection subtasks on sampled CT slices, largely alleviating the curse of dimensionality issue.
no code implementations • 31 Jul 2014 • Amal Farag, Le Lu, Evrim Turkbey, Jiamin Liu, Ronald M. Summers
Organ segmentation is a prerequisite for a computer-aided diagnosis (CAD) system to detect pathologies and perform quantitative analysis.
no code implementations • 22 Jul 2014 • Holger R. Roth, Jianhua Yao, Le Lu, James Stieger, Joseph E. Burns, Ronald M. Summers
In testing, the CNN is employed to assign individual probabilities for a new set of N random views that are averaged at each ROI to compute a final per-candidate classification probability.
no code implementations • 6 Jun 2014 • Holger R. Roth, Le Lu, Ari Seff, Kevin M. Cherry, Joanne Hoffman, Shijun Wang, Jiamin Liu, Evrim Turkbey, Ronald M. Summers
and 84%/90% at 6 FP/vol.
no code implementations • 16 May 2014 • Meizhu Liu, Le Lu, Xiaojing Ye, Shipeng Yu
Classification is one of the core problems in Computer-Aided Diagnosis (CAD), targeting for early cancer detection using 3D medical imaging interpretation.
1 code implementation • 11 Jul 2013 • Quan Wang, Dijia Wu, Le Lu, Meizhu Liu, Kim L. Boyer, Shaohua Kevin Zhou
The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities.