1 code implementation • 30 Jun 2024 • Jintai Chen, Yaojun Hu, Yue Wang, Yingzhou Lu, Xu Cao, Miao Lin, Hongxia Xu, Jian Wu, Cao Xiao, Jimeng Sun, Lucas Glass, Kexin Huang, Marinka Zitnik, Tianfan Fu
Clinical trials are pivotal for developing new medical treatments, yet they typically pose some risks such as patient mortality, adverse events, and enrollment failure that waste immense efforts spanning over a decade.
no code implementations • 23 Oct 2023 • Cheng Qian, Lucas Glass, Nikos Sidiropoulos
Forecasting project expenses is a crucial step for businesses to avoid budget overruns and project failures.
no code implementations • 30 May 2023 • Brandon Theodorou, Lucas Glass, Cao Xiao, Jimeng Sun
This paper focuses on the trial site selection task and proposes FRAMM, a deep reinforcement learning framework for fair trial site selection.
no code implementations • 2 May 2023 • Xinyan Li, Cheng Qian, Lucas Glass
Respiratory syncytial virus (RSV) is one of the most dangerous respiratory diseases for infants and young children.
no code implementations • 13 Apr 2022 • Rakshith S Srinivasa, Cheng Qian, Brandon Theodorou, Jeffrey Spaeder, Cao Xiao, Lucas Glass, Jimeng Sun
More recently, the issue of diversity and inclusion in clinical trials is gaining importance.
no code implementations • 31 Jan 2022 • Cheng Qian, Kejun Huang, Lucas Glass, Rakshith S. Srinivasa, Jimeng Sun
Tensor completion aims at imputing missing entries from a partially observed tensor.
no code implementations • 11 May 2021 • Cheng Qian, Nikos Kargas, Cao Xiao, Lucas Glass, Nicholas Sidiropoulos, Jimeng Sun
Recovering such missing or noisy (under-reported) elements of the input tensor can be viewed as a generalized tensor completion problem.
1 code implementation • 5 May 2021 • Chaoqi Yang, Cao Xiao, Fenglong Ma, Lucas Glass, Jimeng Sun
On a benchmark dataset, our SafeDrug is relatively shown to reduce DDI by 19. 43% and improves 2. 88% on Jaccard similarity between recommended and actually prescribed drug combinations over previous approaches.
no code implementations • 5 May 2021 • Chaoqi Yang, Cao Xiao, Lucas Glass, Jimeng Sun
Deep learning is revolutionizing predictive healthcare, including recommending medications to patients with complex health conditions.
no code implementations • 5 Mar 2021 • Zhen Lin, Cao Xiao, Lucas Glass, M. Brandon Westover, Jimeng Sun
Despite deep learning (DL) success in classification problems, DL classifiers do not provide a sound mechanism to decide when to refrain from predicting.
2 code implementations • 11 Jan 2021 • Yue Zhao, Zhi Qiao, Cao Xiao, Lucas Glass, Jimeng Sun
PyHealth consists of data preprocessing module, predictive modeling module, and evaluation module.
no code implementations • 15 Jun 2020 • Rakshith S Srinivasa, Cao Xiao, Lucas Glass, Justin Romberg, Jimeng Sun
The attention mechanism has demonstrated superior performance for inference over nodes in graph neural networks (GNNs), however, they result in a high computational burden during both training and inference.
1 code implementation • 30 Apr 2020 • Kexin Huang, Cao Xiao, Lucas Glass, Marinka Zitnik, Jimeng Sun
Here, we present SkipGNN, a graph neural network approach for the prediction of molecular interactions.
1 code implementation • 23 Apr 2020 • Kexin Huang, Cao Xiao, Lucas Glass, Jimeng Sun
Drug target interaction (DTI) prediction is a foundational task for in silico drug discovery, which is costly and time-consuming due to the need of experimental search over large drug compound space.
1 code implementation • 19 Apr 2020 • Kexin Huang, Tianfan Fu, Lucas Glass, Marinka Zitnik, Cao Xiao, Jimeng Sun
Accurate prediction of drug-target interactions (DTI) is crucial for drug discovery.
Ranked #2 on Drug Discovery on KIBA
no code implementations • 1 Jul 2019 • Fan Zhang, Tong Wu, Yunlong Wang, Yong Cai, Cao Xiao, Emily Zhao, Lucas Glass, Jimeng Sun
Many computational models were proposed to extract temporal patterns from clinical time series for each patient and among patient group for predictive healthcare.
no code implementations • 1 Jul 2019 • Kezi Yu, Yunlong Wang, Yong Cai, Cao Xiao, Emily Zhao, Lucas Glass, Jimeng Sun
Rare diseases affecting 350 million individuals are commonly associated with delay in diagnosis or misdiagnosis.