no code implementations • 3 Apr 2023 • Chuang Niu, Qing Lyu, Christopher D. Carothers, Parisa Kaviani, Josh Tan, Pingkun Yan, Mannudeep K. Kalra, Christopher T. Whitlow, Ge Wang
Here we propose the first-of-its-kind medical multimodal-multitask foundation model (M3FM) with an emphasis on lung cancer screening.
no code implementations • 24 Mar 2022 • Chuang Niu, Giridhar Dasegowda, Pingkun Yan, Mannudeep K. Kalra, Ge Wang
Although radiographs are the most frequently used worldwide due to their cost-effectiveness and widespread accessibility, the structural superposition along the x-ray paths often renders suspicious or concerning lung nodules difficult to detect.
no code implementations • 30 Nov 2020 • Ti Bai, Biling Wang, Dan Nguyen, Bao Wang, Bin Dong, Wenxiang Cong, Mannudeep K. Kalra, Steve Jiang
However, there exists two challenges regarding the DL-based denoisers: 1) a trained model typically does not generate different image candidates with different noise-resolution tradeoffs which sometimes are needed for different clinical tasks; 2) the model generalizability might be an issue when the noise level in the testing images is different from that in the training dataset.
no code implementations • 26 Nov 2020 • Aoxiao Zhong, Xiang Li, Dufan Wu, Hui Ren, Kyungsang Kim, YoungGon Kim, Varun Buch, Nir Neumark, Bernardo Bizzo, Won Young Tak, Soo Young Park, Yu Rim Lee, Min Kyu Kang, Jung Gil Park, Byung Seok Kim, Woo Jin Chung, Ning Guo, Ittai Dayan, Mannudeep K. Kalra, Quanzheng Li
These results demonstrate our deep metric learning based image retrieval model is highly efficient in the CXR retrieval, diagnosis and prognosis, and thus has great clinical value for the treatment and management of COVID-19 patients.
1 code implementation • 26 Sep 2020 • Young-Gon Kim, Kyungsang Kim, Dufan Wu, Hui Ren, Won Young Tak, Soo Young Park, Yu Rim Lee, Min Kyu Kang, Jung Gil Park, Byung Seok Kim, Woo Jin Chung, Mannudeep K. Kalra, Quanzheng Li
A segmentation model to separate left and right lung is firstly applied, and then a carina and left hilum detection network is used, which are the clinical landmarks to separate the upper and lower lungs.
2 code implementations • 16 Aug 2020 • Hanqing Chao, Hongming Shan, Fatemeh Homayounieh, Ramandeep Singh, Ruhani Doda Khera, Hengtao Guo, Timothy Su, Ge Wang, Mannudeep K. Kalra, Pingkun Yan
Cancer patients have a higher risk of cardiovascular disease (CVD) mortality than the general population.
1 code implementation • 20 Jul 2020 • Hanqing Chao, Xi Fang, Jiajin Zhang, Fatemeh Homayounieh, Chiara D. Arru, Subba R. Digumarthy, Rosa Babaei, Hadi K. Mobin, Iman Mohseni, Luca Saba, Alessandro Carriero, Zeno Falaschi, Alessio Pasche, Ge Wang, Mannudeep K. Kalra, Pingkun Yan
Management of high-risk patients with early intervention is a key to lower the fatality rate of COVID-19 pneumonia, as a majority of patients recover naturally.
no code implementations • 8 Jul 2020 • Florin C. Ghesu, Bogdan Georgescu, Awais Mansoor, Youngjin Yoo, Eli Gibson, R. S. Vishwanath, Abishek Balachandran, James M. Balter, Yue Cao, Ramandeep Singh, Subba R. Digumarthy, Mannudeep K. Kalra, Sasa Grbic, Dorin Comaniciu
In our experiments we demonstrate that sample rejection based on the predicted uncertainty can significantly improve the ROC-AUC for various tasks, e. g., by 8% to 0. 91 with an expected rejection rate of under 25% for the classification of different abnormalities in chest radiographs.
1 code implementation • 6 May 2020 • Tahereh Javaheri, Morteza Homayounfar, Zohreh Amoozgar, Reza Reiazi, Fatemeh Homayounieh, Engy Abbas, Azadeh Laali, Amir Reza Radmard, Mohammad Hadi Gharib, Seyed Ali Javad Mousavi, Omid Ghaemi, Rosa Babaei, Hadi Karimi Mobin, Mehdi Hosseinzadeh, Rana Jahanban-Esfahlan, Khaled Seidi, Mannudeep K. Kalra, Guanglan Zhang, L. T. Chitkushev, Benjamin Haibe-Kains, Reza Malekzadeh, Reza Rawassizadeh
In order to facilitate the detection of Covid-19 globally and assist radiologists and physicians in the screening process, we are releasing all algorithms and parametric details in an open-source format.
Ranked #1 on COVID-19 Diagnosis on
no code implementations • 18 Jun 2019 • Florin C. Ghesu, Bogdan Georgescu, Eli Gibson, Sebastian Guendel, Mannudeep K. Kalra, Ramandeep Singh, Subba R. Digumarthy, Sasa Grbic, Dorin Comaniciu
We argue that explicitly learning the classification uncertainty as an orthogonal measure to the predicted output, is essential to account for the inherent variability characteristic of this data.
1 code implementation • 20 Feb 2019 • Hengtao Guo, Uwe Kruger, Ge Wang, Mannudeep K. Kalra, Pingkun Yan
Recent studies have highlighted the high correlation between cardiovascular diseases (CVD) and lung cancer, and both are associated with significant morbidity and mortality.
1 code implementation • 17 Jan 2019 • Fenglei Fan, Hongming Shan, Mannudeep K. Kalra, Ramandeep Singh, Guhan Qian, Matthew Getzin, Yueyang Teng, Juergen Hahn, Ge Wang
Inspired by complexity and diversity of biological neurons, our group proposed quadratic neurons by replacing the inner product in current artificial neurons with a quadratic operation on input data, thereby enhancing the capability of an individual neuron.
1 code implementation • 8 Nov 2018 • Hongming Shan, Atul Padole, Fatemeh Homayounieh, Uwe Kruger, Ruhani Doda Khera, Chayanin Nitiwarangkul, Mannudeep K. Kalra, Ge Wang
Here we design a novel neural network architecture for low-dose CT (LDCT) and compare it with commercial iterative reconstruction methods used for standard of care CT.
no code implementations • 19 Oct 2018 • Pingkun Yan, Hengtao Guo, Ge Wang, Ruben De Man, Mannudeep K. Kalra
In this paper, we propose a deep learning based method, which takes both chest LDCT image patches and coronary artery calcification risk scores as input, for direct prediction of mortality risk of lung cancer subjects.
no code implementations • 15 Feb 2018 • Hongming Shan, Yi Zhang, Qingsong Yang, Uwe Kruger, Mannudeep K. Kalra, Ling Sun, Wenxiang Cong, Ge Wang
Based on the transfer learning from 2D to 3D, the 3D network converges faster and achieves a better denoising performance than that trained from scratch.
9 code implementations • 3 Aug 2017 • Qingsong Yang, Pingkun Yan, Yanbo Zhang, Hengyong Yu, Yongyi Shi, Xuanqin Mou, Mannudeep K. Kalra, Ge Wang
In this paper, we introduce a new CT image denoising method based on the generative adversarial network (GAN) with Wasserstein distance and perceptual similarity.
no code implementations • 22 Feb 2017 • Qingsong Yang, Pingkun Yan, Mannudeep K. Kalra, Ge Wang
Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence.
1 code implementation • 1 Feb 2017 • Hu Chen, Yi Zhang, Mannudeep K. Kalra, Feng Lin, Yang Chen, Peixi Liao, Jiliu Zhou, Ge Wang
Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field.