Search Results for author: Marc Modat

Found 35 papers, 17 papers with code

Generative AI for Medical Imaging: extending the MONAI Framework

2 code implementations27 Jul 2023 Walter H. L. Pinaya, Mark S. Graham, Eric Kerfoot, Petru-Daniel Tudosiu, Jessica Dafflon, Virginia Fernandez, Pedro Sanchez, Julia Wolleb, Pedro F. da Costa, Ashay Patel, Hyungjin Chung, Can Zhao, Wei Peng, Zelong Liu, Xueyan Mei, Oeslle Lucena, Jong Chul Ye, Sotirios A. Tsaftaris, Prerna Dogra, Andrew Feng, Marc Modat, Parashkev Nachev, Sebastien Ourselin, M. Jorge Cardoso

We have implemented these models in a generalisable fashion, illustrating that their results can be extended to 2D or 3D scenarios, including medical images with different modalities (like CT, MRI, and X-Ray data) and from different anatomical areas.

Anomaly Detection Denoising +2

Driving Points Prediction For Abdominal Probabilistic Registration

1 code implementation5 Aug 2022 Samuel Joutard, Reuben Dorent, Sebastien Ourselin, Tom Vercauteren, Marc Modat

Among the various registration methods proposed for this task, probabilistic displacement registration models estimate displacement distribution for a subset of points by comparing feature vectors of points from the two images.

Anatomy

Federated Learning Enables Big Data for Rare Cancer Boundary Detection

1 code implementation22 Apr 2022 Sarthak Pati, Ujjwal Baid, Brandon Edwards, Micah Sheller, Shih-han Wang, G Anthony Reina, Patrick Foley, Alexey Gruzdev, Deepthi Karkada, Christos Davatzikos, Chiharu Sako, Satyam Ghodasara, Michel Bilello, Suyash Mohan, Philipp Vollmuth, Gianluca Brugnara, Chandrakanth J Preetha, Felix Sahm, Klaus Maier-Hein, Maximilian Zenk, Martin Bendszus, Wolfgang Wick, Evan Calabrese, Jeffrey Rudie, Javier Villanueva-Meyer, Soonmee Cha, Madhura Ingalhalikar, Manali Jadhav, Umang Pandey, Jitender Saini, John Garrett, Matthew Larson, Robert Jeraj, Stuart Currie, Russell Frood, Kavi Fatania, Raymond Y Huang, Ken Chang, Carmen Balana, Jaume Capellades, Josep Puig, Johannes Trenkler, Josef Pichler, Georg Necker, Andreas Haunschmidt, Stephan Meckel, Gaurav Shukla, Spencer Liem, Gregory S Alexander, Joseph Lombardo, Joshua D Palmer, Adam E Flanders, Adam P Dicker, Haris I Sair, Craig K Jones, Archana Venkataraman, Meirui Jiang, Tiffany Y So, Cheng Chen, Pheng Ann Heng, Qi Dou, Michal Kozubek, Filip Lux, Jan Michálek, Petr Matula, Miloš Keřkovský, Tereza Kopřivová, Marek Dostál, Václav Vybíhal, Michael A Vogelbaum, J Ross Mitchell, Joaquim Farinhas, Joseph A Maldjian, Chandan Ganesh Bangalore Yogananda, Marco C Pinho, Divya Reddy, James Holcomb, Benjamin C Wagner, Benjamin M Ellingson, Timothy F Cloughesy, Catalina Raymond, Talia Oughourlian, Akifumi Hagiwara, Chencai Wang, Minh-Son To, Sargam Bhardwaj, Chee Chong, Marc Agzarian, Alexandre Xavier Falcão, Samuel B Martins, Bernardo C A Teixeira, Flávia Sprenger, David Menotti, Diego R Lucio, Pamela Lamontagne, Daniel Marcus, Benedikt Wiestler, Florian Kofler, Ivan Ezhov, Marie Metz, Rajan Jain, Matthew Lee, Yvonne W Lui, Richard McKinley, Johannes Slotboom, Piotr Radojewski, Raphael Meier, Roland Wiest, Derrick Murcia, Eric Fu, Rourke Haas, John Thompson, David Ryan Ormond, Chaitra Badve, Andrew E Sloan, Vachan Vadmal, Kristin Waite, Rivka R Colen, Linmin Pei, Murat AK, Ashok Srinivasan, J Rajiv Bapuraj, Arvind Rao, Nicholas Wang, Ota Yoshiaki, Toshio Moritani, Sevcan Turk, Joonsang Lee, Snehal Prabhudesai, Fanny Morón, Jacob Mandel, Konstantinos Kamnitsas, Ben Glocker, Luke V M Dixon, Matthew Williams, Peter Zampakis, Vasileios Panagiotopoulos, Panagiotis Tsiganos, Sotiris Alexiou, Ilias Haliassos, Evangelia I Zacharaki, Konstantinos Moustakas, Christina Kalogeropoulou, Dimitrios M Kardamakis, Yoon Seong Choi, Seung-Koo Lee, Jong Hee Chang, Sung Soo Ahn, Bing Luo, Laila Poisson, Ning Wen, Pallavi Tiwari, Ruchika Verma, Rohan Bareja, Ipsa Yadav, Jonathan Chen, Neeraj Kumar, Marion Smits, Sebastian R van der Voort, Ahmed Alafandi, Fatih Incekara, Maarten MJ Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W Schouten, Hendrikus J Dubbink, Arnaud JPE Vincent, Martin J van den Bent, Pim J French, Stefan Klein, Yading Yuan, Sonam Sharma, Tzu-Chi Tseng, Saba Adabi, Simone P Niclou, Olivier Keunen, Ann-Christin Hau, Martin Vallières, David Fortin, Martin Lepage, Bennett Landman, Karthik Ramadass, Kaiwen Xu, Silky Chotai, Lola B Chambless, Akshitkumar Mistry, Reid C Thompson, Yuriy Gusev, Krithika Bhuvaneshwar, Anousheh Sayah, Camelia Bencheqroun, Anas Belouali, Subha Madhavan, Thomas C Booth, Alysha Chelliah, Marc Modat, Haris Shuaib, Carmen Dragos, Aly Abayazeed, Kenneth Kolodziej, Michael Hill, Ahmed Abbassy, Shady Gamal, Mahmoud Mekhaimar, Mohamed Qayati, Mauricio Reyes, Ji Eun Park, Jihye Yun, Ho Sung Kim, Abhishek Mahajan, Mark Muzi, Sean Benson, Regina G H Beets-Tan, Jonas Teuwen, Alejandro Herrera-Trujillo, Maria Trujillo, William Escobar, Ana Abello, Jose Bernal, Jhon Gómez, Joseph Choi, Stephen Baek, Yusung Kim, Heba Ismael, Bryan Allen, John M Buatti, Aikaterini Kotrotsou, Hongwei Li, Tobias Weiss, Michael Weller, Andrea Bink, Bertrand Pouymayou, Hassan F Shaykh, Joel Saltz, Prateek Prasanna, Sampurna Shrestha, Kartik M Mani, David Payne, Tahsin Kurc, Enrique Pelaez, Heydy Franco-Maldonado, Francis Loayza, Sebastian Quevedo, Pamela Guevara, Esteban Torche, Cristobal Mendoza, Franco Vera, Elvis Ríos, Eduardo López, Sergio A Velastin, Godwin Ogbole, Dotun Oyekunle, Olubunmi Odafe-Oyibotha, Babatunde Osobu, Mustapha Shu'aibu, Adeleye Dorcas, Mayowa Soneye, Farouk Dako, Amber L Simpson, Mohammad Hamghalam, Jacob J Peoples, Ricky Hu, Anh Tran, Danielle Cutler, Fabio Y Moraes, Michael A Boss, James Gimpel, Deepak Kattil Veettil, Kendall Schmidt, Brian Bialecki, Sailaja Marella, Cynthia Price, Lisa Cimino, Charles Apgar, Prashant Shah, Bjoern Menze, Jill S Barnholtz-Sloan, Jason Martin, Spyridon Bakas

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data.

Boundary Detection Federated Learning

Augmentation based unsupervised domain adaptation

no code implementations23 Feb 2022 Mauricio Orbes-Arteaga, Thomas Varsavsky, Lauge Sorensen, Mads Nielsen, Akshay Pai, Sebastien Ourselin, Marc Modat, M Jorge Cardoso

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation.

Anomaly Detection Segmentation +1

Inter Extreme Points Geodesics for End-to-End Weakly Supervised Image Segmentation

1 code implementation1 Jul 2021 Reuben Dorent, Samuel Joutard, Jonathan Shapey, Aaron Kujawa, Marc Modat, Sebastien Ourselin, Tom Vercauteren

We introduce $\textit{InExtremIS}$, a weakly supervised 3D approach to train a deep image segmentation network using particularly weak train-time annotations: only 6 extreme clicks at the boundary of the objects of interest.

Image Segmentation Segmentation +2

Robust joint registration of multiple stains and MRI for multimodal 3D histology reconstruction: Application to the Allen human brain atlas

1 code implementation30 Apr 2021 Adrià Casamitjana, Marco Lorenzi, Sebastiano Ferraris, Loc Peter, Marc Modat, Allison Stevens, Bruce Fischl, Tom Vercauteren, Juan Eugenio Iglesias

The model relies on a spanning tree of latent transforms connecting all the sections and slices of the reference volume, and assumes that the registration between any pair of images can be see as a noisy version of the composition of (possibly inverted) latent transforms connecting the two images.

3D Reconstruction Bayesian Inference

Machine Learning and Glioblastoma: Treatment Response Monitoring Biomarkers in 2021

no code implementations15 Apr 2021 Thomas Booth, Bernice Akpinar, Andrei Roman, Haris Shuaib, Aysha Luis, Alysha Chelliah, Ayisha Al Busaidi, Ayesha Mirchandani, Burcu Alparslan, Nina Mansoor, Keyoumars Ashkan, Sebastien Ourselin, Marc Modat

The small numbers of patient included in studies, the high risk of bias and concerns of applicability in the study designs (particularly in relation to the reference standard and patient selection due to confounding), and the low level of evidence, suggest that limited conclusions can be drawn from the data.

BIG-bench Machine Learning Specificity

Scale factor point spread function matching: Beyond aliasing in image resampling

no code implementations16 Jan 2021 M. Jorge Cardoso, Marc Modat, Tom Vercauteren, Sebastien Ourselin

Imaging devices exploit the Nyquist-Shannon sampling theorem to avoid both aliasing and redundant oversampling by design.

Accessible Data Curation and Analytics for International-Scale Citizen Science Datasets

1 code implementation2 Nov 2020 Benjamin Murray, Eric Kerfoot, Mark S. Graham, Carole H. Sudre, Erika Molteni, Liane S. Canas, Michela Antonelli, Kerstin Klaser, Alessia Visconti, Andrew T. Chan, Paul W. Franks, Richard Davies, Jonathan Wolf, Tim Spector, Claire J. Steves, Marc Modat, Sebastien Ourselin

We present ExeTera, an open source data curation software designed to address scalability challenges and to enable reproducible research across an international research group for datasets such as the Covid Symptom Study dataset.

Knowledge distillation for semi-supervised domain adaptation

no code implementations16 Aug 2019 Mauricio Orbes-Arteaga, Jorge Cardoso, Lauge Sørensen, Christian Igel, Sebastien Ourselin, Marc Modat, Mads Nielsen, Akshay Pai

As a result, their performance is significantly lower on data from unseen sources compared to the performance on data from the same source as the training data.

Domain Adaptation Knowledge Distillation +1

Multi-Domain Adaptation in Brain MRI through Paired Consistency and Adversarial Learning

no code implementations16 Aug 2019 Mauricio Orbes-Arteaga, Thomas Varsavsky, Carole H. Sudre, Zach Eaton-Rosen, Lewis J. Haddow, Lauge Sørensen, Mads Nielsen, Akshay Pai, Sébastien Ourselin, Marc Modat, Parashkev Nachev, M. Jorge Cardoso

Inspired by recent work in semi-supervised learning we introduce a novel method to adapt from one source domain to $n$ target domains (as long as there is paired data covering all domains).

Domain Adaptation

Robust parametric modeling of Alzheimer's disease progression

no code implementations14 Aug 2019 Mostafa Mehdipour Ghazi, Mads Nielsen, Akshay Pai, Marc Modat, M. Jorge Cardoso, Sébastien Ourselin, Lauge Sørensen

Different M-estimators and logistic functions, including a novel type proposed in this study, called modified Stannard, are evaluated on the data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) for robust modeling of volumetric MRI and PET biomarkers, CSF measurements, as well as cognitive tests.

Density Estimation

Hetero-Modal Variational Encoder-Decoder for Joint Modality Completion and Segmentation

1 code implementation25 Jul 2019 Reuben Dorent, Samuel Joutard, Marc Modat, Sébastien Ourselin, Tom Vercauteren

We propose a new deep learning method for tumour segmentation when dealing with missing imaging modalities.

Segmentation

Training recurrent neural networks robust to incomplete data: application to Alzheimer's disease progression modeling

no code implementations17 Mar 2019 Mostafa Mehdipour Ghazi, Mads Nielsen, Akshay Pai, M. Jorge Cardoso, Marc Modat, Sebastien Ourselin, Lauge Sørensen

The proposed LSTM algorithm is applied to model the progression of Alzheimer's disease (AD) using six volumetric magnetic resonance imaging (MRI) biomarkers, i. e., volumes of ventricles, hippocampus, whole brain, fusiform, middle temporal gyrus, and entorhinal cortex, and it is compared to standard LSTM networks with data imputation and a parametric, regression-based DPM method.

Hippocampus Imputation

Grey matter sublayer thickness estimation in themouse cerebellum

1 code implementation8 Jan 2019 Da Ma, Manuel J. Cardoso, Maria A. Zuluaga, Marc Modat, Nick. Powell, Frances Wiseman, Victor Tybulewicz, Elizabeth Fisher, Mark. F. Lythgoe, Sebastien Ourselin

In this work, we introduce a framework to extract the Purkinje layer within the grey matter, enabling the estimation of the thickness of the cerebellar grey matter, the granular layer and molecular layer from gadolinium-enhanced ex vivo mouse brain MRI.

PADDIT: Probabilistic Augmentation of Data using Diffeomorphic Image Transformation

no code implementations3 Oct 2018 Mauricio Orbes Arteaga, Lauge Sørensen, M. Jorge Cardoso, Marc Modat, Sebastien Ourselin, Stefan Sommer, Mads Nielsen, Christian Igel, Akshay Pai

For proper generalization performance of convolutional neural networks (CNNs) in medical image segmentation, the learnt features should be invariant under particular non-linear shape variations of the input.

Image Segmentation Medical Image Segmentation +1

Deep Boosted Regression for MR to CT Synthesis

no code implementations22 Aug 2018 Kerstin Kläser, Pawel Markiewicz, Marta Ranzini, Wenqi Li, Marc Modat, Brian F. Hutton, David Atkinson, Kris Thielemans, M. Jorge Cardoso, Sebastien Ourselin

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification.

Computed Tomography (CT) Image Reconstruction +1

Simultaneous synthesis of FLAIR and segmentation of white matter hypointensities from T1 MRIs

no code implementations20 Aug 2018 Mauricio Orbes-Arteaga, M. Jorge Cardoso, Lauge Sørensen, Marc Modat, Sébastien Ourselin, Mads Nielsen, Akshay Pai

Segmenting vascular pathologies such as white matter lesions in Brain magnetic resonance images (MRIs) require acquisition of multiple sequences such as T1-weighted (T1-w) --on which lesions appear hypointense-- and fluid attenuated inversion recovery (FLAIR) sequence --where lesions appear hyperintense--.

Imputation Segmentation

Weakly-Supervised Convolutional Neural Networks for Multimodal Image Registration

no code implementations9 Jul 2018 Yipeng Hu, Marc Modat, Eli Gibson, Wenqi Li, Nooshin Ghavami, Ester Bonmati, Guotai Wang, Steven Bandula, Caroline M. Moore, Mark Emberton, Sébastien Ourselin, J. Alison Noble, Dean C. Barratt, Tom Vercauteren

A median target registration error of 3. 6 mm on landmark centroids and a median Dice of 0. 87 on prostate glands are achieved from cross-validation experiments, in which 108 pairs of multimodal images from 76 patients were tested with high-quality anatomical labels.

Image Registration

Joint registration and synthesis using a probabilistic model for alignment of MRI and histological sections

no code implementations16 Jan 2018 Juan Eugenio Iglesias, Marc Modat, Loic Peter, Allison Stevens, Roberto Annunziata, Tom Vercauteren, Ed Lein, Bruce Fischl, Sebastien Ourselin

Here, we overcome this limitation with a probabilistic method that simultaneously solves for registration and synthesis directly on the target images, without any training data.

Bayesian Inference

Label-driven weakly-supervised learning for multimodal deformable image registration

1 code implementation5 Nov 2017 Yipeng Hu, Marc Modat, Eli Gibson, Nooshin Ghavami, Ester Bonmati, Caroline M. Moore, Mark Emberton, J. Alison Noble, Dean C. Barratt, Tom Vercauteren

Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms.

Image Registration Weakly-supervised Learning

NiftyNet: a deep-learning platform for medical imaging

10 code implementations11 Sep 2017 Eli Gibson, Wenqi Li, Carole Sudre, Lucas Fidon, Dzhoshkun I. Shakir, Guotai Wang, Zach Eaton-Rosen, Robert Gray, Tom Doel, Yipeng Hu, Tom Whyntie, Parashkev Nachev, Marc Modat, Dean C. Barratt, Sébastien Ourselin, M. Jorge Cardoso, Tom Vercauteren

NiftyNet provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications.

Data Augmentation Image Generation +4

Part-to-whole Registration of Histology and MRI using Shape Elements

no code implementations27 Aug 2017 Jonas Pichat, Juan Eugenio Iglesias, Sotiris Nousias, Tarek Yousry, Sebastien Ourselin, Marc Modat

We propose here a novel automatic approach to the joint problem of multimodal registration between histology and MRI, when only a fraction of tissue is available from histology.

Image Registration

Automatic structural parcellation of mouse brain MRI using multi-atlas label fusion

1 code implementation27 Jan 2014 Da Ma, Manuel J. Cardoso, Marc Modat, Nick Powell, Jack Wells, Holly Holmes, Frances Wiseman, Victor Tybulewicz, Elizabeth Fisher, Mark F. Lythgoe, Sébastien Ourselin

The segmentation accuracy of the multi-atlas framework was evaluated using publicly available mouse brain atlas databases with pre-segmented manually labelled anatomical structures as the gold standard, and optimised parameters were obtained for the STEPS algorithm in the label fusion to achieve the best segmentation accuracy.

Segmentation

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