Search Results for author: Maria Vakalopoulou

Found 37 papers, 19 papers with code

SI-MIL: Taming Deep MIL for Self-Interpretability in Gigapixel Histopathology

1 code implementation22 Dec 2023 Saarthak Kapse, Pushpak Pati, Srijan Das, Jingwei Zhang, Chao Chen, Maria Vakalopoulou, Joel Saltz, Dimitris Samaras, Rajarsi R. Gupta, Prateek Prasanna

Introducing interpretability and reasoning into Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) analysis is challenging, given the complexity of gigapixel slides.

Multiple Instance Learning

Certification of Deep Learning Models for Medical Image Segmentation

no code implementations5 Oct 2023 Othmane Laousy, Alexandre Araujo, Guillaume Chassagnon, Nikos Paragios, Marie-Pierre Revel, Maria Vakalopoulou

In this paper, we present for the first time a certified segmentation baseline for medical imaging based on randomized smoothing and diffusion models.

Denoising Image Segmentation +3

On the detection of Out-Of-Distribution samples in Multiple Instance Learning

1 code implementation11 Sep 2023 Loïc Le Bescond, Maria Vakalopoulou, Stergios Christodoulidis, Fabrice André, Hugues Talbot

While significant efforts have been devoted to OOD detection in classical supervised settings, the context of weakly supervised learning, particularly the Multiple Instance Learning (MIL) framework, remains under-explored.

Multiple Instance Learning Out of Distribution (OOD) Detection +1

Spatio-Temporal Analysis of Patient-Derived Organoid Videos Using Deep Learning for the Prediction of Drug Efficacy

no code implementations28 Aug 2023 Leo Fillioux, Emilie Gontran, Jérôme Cartry, Jacques RR Mathieu, Sabrina Bedja, Alice Boilève, Paul-Henry Cournède, Fanny Jaulin, Stergios Christodoulidis, Maria Vakalopoulou

In particular, PDOs are attracting interest in the field of Functional Precision Medicine (FPM), which is based upon an ex-vivo drug test in which living tumor cells (such as PDOs) from a specific patient are exposed to a panel of anti-cancer drugs.

Multiple Instance Learning

SAM-Path: A Segment Anything Model for Semantic Segmentation in Digital Pathology

no code implementations12 Jul 2023 Jingwei Zhang, Ke Ma, Saarthak Kapse, Joel Saltz, Maria Vakalopoulou, Prateek Prasanna, Dimitris Samaras

On these two datasets, the proposed additional pathology foundation model further achieves a relative improvement of 5. 07% to 5. 12% in Dice score and 4. 50% to 8. 48% in IOU.

Instance Segmentation Segmentation +1

Towards Better Certified Segmentation via Diffusion Models

no code implementations16 Jun 2023 Othmane Laousy, Alexandre Araujo, Guillaume Chassagnon, Marie-Pierre Revel, Siddharth Garg, Farshad Khorrami, Maria Vakalopoulou

The robustness of image segmentation has been an important research topic in the past few years as segmentation models have reached production-level accuracy.

Autonomous Driving Image Segmentation +2

MEDIMP: 3D Medical Images with clinical Prompts from limited tabular data for renal transplantation

1 code implementation22 Mar 2023 Leo Milecki, Vicky Kalogeiton, Sylvain Bodard, Dany Anglicheau, Jean-Michel Correas, Marc-Olivier Timsit, Maria Vakalopoulou

Our goal is to learn meaningful manifolds of renal transplant DCE MRI, interesting for the prognosis of the transplant or patient status (2, 3, and 4 years after the transplant), fully exploiting the limited available multi-modal data most efficiently.

Contrastive Learning Representation Learning

Prompt-MIL: Boosting Multi-Instance Learning Schemes via Task-specific Prompt Tuning

1 code implementation21 Mar 2023 Jingwei Zhang, Saarthak Kapse, Ke Ma, Prateek Prasanna, Joel Saltz, Maria Vakalopoulou, Dimitris Samaras

Compared to conventional full fine-tuning approaches, we fine-tune less than 1. 3% of the parameters, yet achieve a relative improvement of 1. 29%-13. 61% in accuracy and 3. 22%-27. 18% in AUROC and reduce GPU memory consumption by 38%-45% while training 21%-27% faster.

Precise Location Matching Improves Dense Contrastive Learning in Digital Pathology

1 code implementation23 Dec 2022 Jingwei Zhang, Saarthak Kapse, Ke Ma, Prateek Prasanna, Maria Vakalopoulou, Joel Saltz, Dimitris Samaras

Our method outperforms previous dense matching methods by up to 7. 2% in average precision for detection and 5. 6% in average precision for instance segmentation tasks.

Contrastive Learning Instance Segmentation +2

Artifact Removal in Histopathology Images

no code implementations29 Nov 2022 Cameron Dahan, Stergios Christodoulidis, Maria Vakalopoulou, Joseph Boyd

In the clinical setting of histopathology, whole-slide image (WSI) artifacts frequently arise, distorting regions of interest, and having a pernicious impact on WSI analysis.

Image-to-Image Translation Translation

Multi-center anatomical segmentation with heterogeneous labels via landmark-based models

1 code implementation14 Nov 2022 Nicolás Gaggion, Maria Vakalopoulou, Diego H. Milone, Enzo Ferrante

Learning anatomical segmentation from heterogeneous labels in multi-center datasets is a common situation encountered in clinical scenarios, where certain anatomical structures are only annotated in images coming from particular medical centers, but not in the full database.

Landmark-based segmentation Memorization +1

Region-guided CycleGANs for Stain Transfer in Whole Slide Images

1 code implementation26 Aug 2022 Joseph Boyd, Irène Villa, Marie-Christine Mathieu, Eric Deutsch, Nikos Paragios, Maria Vakalopoulou, Stergios Christodoulidis

We present a use case on whole slide images, where an IHC stain provides an experimentally generated signal for metastatic cells.

whole slide images

Gigapixel Whole-Slide Images Classification using Locally Supervised Learning

1 code implementation17 Jul 2022 Jingwei Zhang, Xin Zhang, Ke Ma, Rajarsi Gupta, Joel Saltz, Maria Vakalopoulou, Dimitris Samaras

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses.

Classification Multiple Instance Learning +1

Test-time image-to-image translation ensembling improves out-of-distribution generalization in histopathology

no code implementations20 Jun 2022 Marin Scalbert, Maria Vakalopoulou, Florent Couzinié-Devy

In this paper, to enhance robustness on unseen target protocols, we propose a new test-time data augmentation based on multi domain image-to-image translation.

Data Augmentation Domain Generalization +4

The Brain Tumor Sequence Registration (BraTS-Reg) Challenge: Establishing Correspondence Between Pre-Operative and Follow-up MRI Scans of Diffuse Glioma Patients

no code implementations13 Dec 2021 Bhakti Baheti, Satrajit Chakrabarty, Hamed Akbari, Michel Bilello, Benedikt Wiestler, Julian Schwarting, Evan Calabrese, Jeffrey Rudie, Syed Abidi, Mina Mousa, Javier Villanueva-Meyer, Brandon K. K. Fields, Florian Kofler, Russell Takeshi Shinohara, Juan Eugenio Iglesias, Tony C. W. Mok, Albert C. S. Chung, Marek Wodzinski, Artur Jurgas, Niccolo Marini, Manfredo Atzori, Henning Muller, Christoph Grobroehmer, Hanna Siebert, Lasse Hansen, Mattias P. Heinrich, Luca Canalini, Jan Klein, Annika Gerken, Stefan Heldmann, Alessa Hering, Horst K. Hahn, Mingyuan Meng, Lei Bi, Dagan Feng, Jinman Kim, Ramy A. Zeineldin, Mohamed E. Karar, Franziska Mathis-Ullrich, Oliver Burgert, Javid Abderezaei, Aymeric Pionteck, Agamdeep Chopra, Mehmet Kurt, Kewei Yan, Yonghong Yan, Zhe Tang, Jianqiang Ma, Sahar Almahfouz Nasser, Nikhil Cherian Kurian, Mohit Meena, Saqib Shamsi, Amit Sethi, Nicholas J. Tustison, Brian B. Avants, Philip Cook, James C. Gee, Lin Tian, Hastings Greer, Marc Niethammer, Andrew Hoopes, Malte Hoffmann, Adrian V. Dalca, Stergios Christodoulidis, Theo Estiene, Maria Vakalopoulou, Nikos Paragios, Daniel S. Marcus, Christos Davatzikos, Aristeidis Sotiras, Bjoern Menze, Spyridon Bakas, Diana Waldmannstetter

Registration of longitudinal brain MRI scans containing pathologies is challenging due to dramatic changes in tissue appearance.

Descriptive Image Registration +1

Self-Supervised Representation Learning using Visual Field Expansion on Digital Pathology

1 code implementation7 Sep 2021 Joseph Boyd, Mykola Liashuha, Eric Deutsch, Nikos Paragios, Stergios Christodoulidis, Maria Vakalopoulou

In this study, we propose a novel generative framework that can learn powerful representations for such tiles by learning to plausibly expand their visual field.

Representation Learning

Multi-Source domain adaptation via supervised contrastive learning and confident consistency regularization

no code implementations30 Jun 2021 Marin Scalbert, Maria Vakalopoulou, Florent Couzinié-Devy

Multi-Source Unsupervised Domain Adaptation (multi-source UDA) aims to learn a model from several labeled source domains while performing well on a different target domain where only unlabeled data are available at training time.

Contrastive Learning Multi-Source Unsupervised Domain Adaptation +1

Weakly supervised pan-cancer segmentation tool

no code implementations10 May 2021 Marvin Lerousseau, Marion Classe, Enzo Battistella, Théo Estienne, Théophraste Henry, Amaury Leroy, Roger Sun, Maria Vakalopoulou, Jean-Yves Scoazec, Eric Deutsch, Nikos Paragios

The vast majority of semantic segmentation approaches rely on pixel-level annotations that are tedious and time consuming to obtain and suffer from significant inter and intra-expert variability.

Segmentation Tumor Segmentation

Self-Supervised Nuclei Segmentation in Histopathological Images Using Attention

1 code implementation16 Jul 2020 Mihir Sahasrabudhe, Stergios Christodoulidis, Roberto Salgado, Stefan Michiels, Sherene Loi, Fabrice André, Nikos Paragios, Maria Vakalopoulou

We show that the identification of the magnification level for tiles can generate a preliminary self-supervision signal to locate nuclei.

Segmentation

Weakly supervised multiple instance learning histopathological tumor segmentation

1 code implementation10 Apr 2020 Marvin Lerousseau, Maria Vakalopoulou, Marion Classe, Julien Adam, Enzo Battistella, Alexandre Carré, Théo Estienne, Théophraste Henry, Eric Deutsch, Nikos Paragios

In this paper, we propose a weakly supervised framework for whole slide imaging segmentation that relies on standard clinical annotations, available in most medical systems.

Histopathological Segmentation Image Segmentation +5

Detecting Urban Changes with Recurrent Neural Networks from Multitemporal Sentinel-2 Data

4 code implementations17 Oct 2019 Maria Papadomanolaki, Sagar Verma, Maria Vakalopoulou, Siddharth Gupta, Konstantinos Karantzalos

\begin{abstract} The advent of multitemporal high resolution data, like the Copernicus Sentinel-2, has enhanced significantly the potential of monitoring the earth's surface and environmental dynamics.

Change Detection

U-ReSNet: Ultimate coupling of Registration and Segmentation with deep Nets

1 code implementation10 Oct 2019 Théo Estienne, Maria Vakalopoulou, Stergios Christodoulidis, Enzo Battistella, Marvin Lerousseau, Alexandre Carre, Guillaume Klausner, Roger Sun, Charlotte Robert, Stavroula Mougiakakou, Nikos Paragios, Eric Deutsch

We evaluated the proposed architecture using the publicly available OASIS 3 dataset, measuring the dice coefficient metric for both registration and segmentation tasks.

Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge

1 code implementation5 Nov 2018 Spyridon Bakas, Mauricio Reyes, Andras Jakab, Stefan Bauer, Markus Rempfler, Alessandro Crimi, Russell Takeshi Shinohara, Christoph Berger, Sung Min Ha, Martin Rozycki, Marcel Prastawa, Esther Alberts, Jana Lipkova, John Freymann, Justin Kirby, Michel Bilello, Hassan Fathallah-Shaykh, Roland Wiest, Jan Kirschke, Benedikt Wiestler, Rivka Colen, Aikaterini Kotrotsou, Pamela Lamontagne, Daniel Marcus, Mikhail Milchenko, Arash Nazeri, Marc-Andre Weber, Abhishek Mahajan, Ujjwal Baid, Elizabeth Gerstner, Dongjin Kwon, Gagan Acharya, Manu Agarwal, Mahbubul Alam, Alberto Albiol, Antonio Albiol, Francisco J. Albiol, Varghese Alex, Nigel Allinson, Pedro H. A. Amorim, Abhijit Amrutkar, Ganesh Anand, Simon Andermatt, Tal Arbel, Pablo Arbelaez, Aaron Avery, Muneeza Azmat, Pranjal B., W Bai, Subhashis Banerjee, Bill Barth, Thomas Batchelder, Kayhan Batmanghelich, Enzo Battistella, Andrew Beers, Mikhail Belyaev, Martin Bendszus, Eze Benson, Jose Bernal, Halandur Nagaraja Bharath, George Biros, Sotirios Bisdas, James Brown, Mariano Cabezas, Shilei Cao, Jorge M. Cardoso, Eric N Carver, Adrià Casamitjana, Laura Silvana Castillo, Marcel Catà, Philippe Cattin, Albert Cerigues, Vinicius S. Chagas, Siddhartha Chandra, Yi-Ju Chang, Shiyu Chang, Ken Chang, Joseph Chazalon, Shengcong Chen, Wei Chen, Jefferson W. Chen, Zhaolin Chen, Kun Cheng, Ahana Roy Choudhury, Roger Chylla, Albert Clérigues, Steven Colleman, Ramiro German Rodriguez Colmeiro, Marc Combalia, Anthony Costa, Xiaomeng Cui, Zhenzhen Dai, Lutao Dai, Laura Alexandra Daza, Eric Deutsch, Changxing Ding, Chao Dong, Shidu Dong, Wojciech Dudzik, Zach Eaton-Rosen, Gary Egan, Guilherme Escudero, Théo Estienne, Richard Everson, Jonathan Fabrizio, Yong Fan, Longwei Fang, Xue Feng, Enzo Ferrante, Lucas Fidon, Martin Fischer, Andrew P. French, Naomi Fridman, Huan Fu, David Fuentes, Yaozong Gao, Evan Gates, David Gering, Amir Gholami, Willi Gierke, Ben Glocker, Mingming Gong, Sandra González-Villá, T. Grosges, Yuanfang Guan, Sheng Guo, Sudeep Gupta, Woo-Sup Han, Il Song Han, Konstantin Harmuth, Huiguang He, Aura Hernández-Sabaté, Evelyn Herrmann, Naveen Himthani, Winston Hsu, Cheyu Hsu, Xiaojun Hu, Xiaobin Hu, Yan Hu, Yifan Hu, Rui Hua, Teng-Yi Huang, Weilin Huang, Sabine Van Huffel, Quan Huo, Vivek HV, Khan M. Iftekharuddin, Fabian Isensee, Mobarakol Islam, Aaron S. Jackson, Sachin R. Jambawalikar, Andrew Jesson, Weijian Jian, Peter Jin, V Jeya Maria Jose, Alain Jungo, B Kainz, Konstantinos Kamnitsas, Po-Yu Kao, Ayush Karnawat, Thomas Kellermeier, Adel Kermi, Kurt Keutzer, Mohamed Tarek Khadir, Mahendra Khened, Philipp Kickingereder, Geena Kim, Nik King, Haley Knapp, Urspeter Knecht, Lisa Kohli, Deren Kong, Xiangmao Kong, Simon Koppers, Avinash Kori, Ganapathy Krishnamurthi, Egor Krivov, Piyush Kumar, Kaisar Kushibar, Dmitrii Lachinov, Tryphon Lambrou, Joon Lee, Chengen Lee, Yuehchou Lee, M Lee, Szidonia Lefkovits, Laszlo Lefkovits, James Levitt, Tengfei Li, Hongwei Li, Hongyang Li, Xiaochuan Li, Yuexiang Li, Heng Li, Zhenye Li, Xiaoyu Li, Zeju Li, Xiaogang Li, Wenqi Li, Zheng-Shen Lin, Fengming Lin, Pietro Lio, Chang Liu, Boqiang Liu, Xiang Liu, Mingyuan Liu, Ju Liu, Luyan Liu, Xavier Llado, Marc Moreno Lopez, Pablo Ribalta Lorenzo, Zhentai Lu, Lin Luo, Zhigang Luo, Jun Ma, Kai Ma, Thomas Mackie, Anant Madabushi, Issam Mahmoudi, Klaus H. Maier-Hein, Pradipta Maji, CP Mammen, Andreas Mang, B. S. Manjunath, Michal Marcinkiewicz, S McDonagh, Stephen McKenna, Richard McKinley, Miriam Mehl, Sachin Mehta, Raghav Mehta, Raphael Meier, Christoph Meinel, Dorit Merhof, Craig Meyer, Robert Miller, Sushmita Mitra, Aliasgar Moiyadi, David Molina-Garcia, Miguel A. B. Monteiro, Grzegorz Mrukwa, Andriy Myronenko, Jakub Nalepa, Thuyen Ngo, Dong Nie, Holly Ning, Chen Niu, Nicholas K Nuechterlein, Eric Oermann, Arlindo Oliveira, Diego D. C. Oliveira, Arnau Oliver, Alexander F. I. Osman, Yu-Nian Ou, Sebastien Ourselin, Nikos Paragios, Moo Sung Park, Brad Paschke, J. Gregory Pauloski, Kamlesh Pawar, Nick Pawlowski, Linmin Pei, Suting Peng, Silvio M. Pereira, Julian Perez-Beteta, Victor M. Perez-Garcia, Simon Pezold, Bao Pham, Ashish Phophalia, Gemma Piella, G. N. Pillai, Marie Piraud, Maxim Pisov, Anmol Popli, Michael P. Pound, Reza Pourreza, Prateek Prasanna, Vesna Prkovska, Tony P. Pridmore, Santi Puch, Élodie Puybareau, Buyue Qian, Xu Qiao, Martin Rajchl, Swapnil Rane, Michael Rebsamen, Hongliang Ren, Xuhua Ren, Karthik Revanuru, Mina Rezaei, Oliver Rippel, Luis Carlos Rivera, Charlotte Robert, Bruce Rosen, Daniel Rueckert, Mohammed Safwan, Mostafa Salem, Joaquim Salvi, Irina Sanchez, Irina Sánchez, Heitor M. Santos, Emmett Sartor, Dawid Schellingerhout, Klaudius Scheufele, Matthew R. Scott, Artur A. Scussel, Sara Sedlar, Juan Pablo Serrano-Rubio, N. Jon Shah, Nameetha Shah, Mazhar Shaikh, B. Uma Shankar, Zeina Shboul, Haipeng Shen, Dinggang Shen, Linlin Shen, Haocheng Shen, Varun Shenoy, Feng Shi, Hyung Eun Shin, Hai Shu, Diana Sima, M Sinclair, Orjan Smedby, James M. Snyder, Mohammadreza Soltaninejad, Guidong Song, Mehul Soni, Jean Stawiaski, Shashank Subramanian, Li Sun, Roger Sun, Jiawei Sun, Kay Sun, Yu Sun, Guoxia Sun, Shuang Sun, Yannick R Suter, Laszlo Szilagyi, Sanjay Talbar, DaCheng Tao, Zhongzhao Teng, Siddhesh Thakur, Meenakshi H Thakur, Sameer Tharakan, Pallavi Tiwari, Guillaume Tochon, Tuan Tran, Yuhsiang M. Tsai, Kuan-Lun Tseng, Tran Anh Tuan, Vadim Turlapov, Nicholas Tustison, Maria Vakalopoulou, Sergi Valverde, Rami Vanguri, Evgeny Vasiliev, Jonathan Ventura, Luis Vera, Tom Vercauteren, C. A. Verrastro, Lasitha Vidyaratne, Veronica Vilaplana, Ajeet Vivekanandan, Qian Wang, Chiatse J. Wang, Wei-Chung Wang, Duo Wang, Ruixuan Wang, Yuanyuan Wang, Chunliang Wang, Guotai Wang, Ning Wen, Xin Wen, Leon Weninger, Wolfgang Wick, Shaocheng Wu, Qiang Wu, Yihong Wu, Yong Xia, Yanwu Xu, Xiaowen Xu, Peiyuan Xu, Tsai-Ling Yang, Xiaoping Yang, Hao-Yu Yang, Junlin Yang, Haojin Yang, Guang Yang, Hongdou Yao, Xujiong Ye, Changchang Yin, Brett Young-Moxon, Jinhua Yu, Xiangyu Yue, Songtao Zhang, Angela Zhang, Kun Zhang, Xue-jie Zhang, Lichi Zhang, Xiaoyue Zhang, Yazhuo Zhang, Lei Zhang, Jian-Guo Zhang, Xiang Zhang, Tianhao Zhang, Sicheng Zhao, Yu Zhao, Xiaomei Zhao, Liang Zhao, Yefeng Zheng, Liming Zhong, Chenhong Zhou, Xiaobing Zhou, Fan Zhou, Hongtu Zhu, Jin Zhu, Ying Zhuge, Weiwei Zong, Jayashree Kalpathy-Cramer, Keyvan Farahani, Christos Davatzikos, Koen van Leemput, Bjoern Menze

This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i. e., 2012-2018.

Brain Tumor Segmentation Survival Prediction +1

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