Search Results for author: Martin G. Frasch

Found 19 papers, 2 papers with code

Brain development dictates energy constraints on neural architecture search: cross-disciplinary insights on optimization strategies

no code implementations3 Oct 2023 Martin G. Frasch

From the developmental neuroscience perspective, I present evidence for the central role of metabolically, rather than prediction-error-optimized neural architecture search (NAS).

Neural Architecture Search

The vagus nerve regulates immunometabolic homeostasis in the ovine fetus near term: impact on terminal ileum

no code implementations27 Mar 2022 Mingju Cao, Shikha Kuthiala, Keven Jason Jean, Hai Lun Liu, Marc Courchesne, Karen Nygard, Patrick Burns, André Desrochers, Gilles Fecteau, Christophe Faure, Martin G. Frasch

Under conditions of moderate fetal inflammation, this is related to higher levels of gut inflammation; the efferent VNS reduces the systemic inflammatory response as well as restores both the levels of glucose and terminal ileum inflammation, but not the insulin levels.

The role of the vagus nerve during fetal development and its relationship with the environment

no code implementations3 Jun 2021 Francesco Cerritelli, Martin G. Frasch, Marta C. Antonelli, Chiara Viglione, Stefano Vecchi, Marco Chiera, Andrea Manzotti

In addition, this paper will focus on which factors (i. e. fetal characteristics and behaviors, maternal lifestyle and pathologies, placental health and dysfunction, labor, incubator conditions, and drug exposure) may have an impact on the development of the vagus during the above-mentioned "critical window" and how.

Heart Rate Variability Management

Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials

no code implementations28 Feb 2021 Martin G. Frasch, Bernd Walter, Christoph Anders, Reinhard Bauer

We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states.


Detection of Maternal and Fetal Stress from the Electrocardiogram with Self-Supervised Representation Learning

2 code implementations3 Nov 2020 Pritam Sarkar, Silvia Lobmaier, Bibiana Fabre, Diego González, Alexander Mueller, Martin G. Frasch, Marta C. Antonelli, Ali Etemad

Our DL models accurately detect the chronic stress exposure group (AUROC=0. 982+/-0. 002), the individual psychological stress score (R2=0. 943+/-0. 009) and FSI at 34 weeks of gestation (R2=0. 946+/-0. 013), as well as the maternal hair cortisol at birth reflecting chronic stress exposure (0. 931+/-0. 006).

Representation Learning Self-Supervised Learning

Monitoring fetal electroencephalogram intrapartum: a systematic literature review

no code implementations27 May 2020 Aude Castel, Yael Frank, John Feltner, Floyd Karp, Catherine Albright, Martin G. Frasch

Background: Studies about the feasibility of monitoring fetal electroencephalogram (fEEG) during labor began in the early 1940s.


Impact of chronic fetal hypoxia and inflammation on cardiac pacemaker cell development

no code implementations24 Feb 2020 Martin G. Frasch, Dino A. Giussani

Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease.

The neonatal sepsis is diminished by cervical vagus nerve stimulation and tracked non-invasively by ECG: a preliminary report in the piglet model

no code implementations10 Feb 2020 Aude Castel, Patrick Burns, Colin Wakefield, Keven. J. Jean, Yael S. Frank, Mingju Cao, Andre Desrochers, Gilles Fecteau, Christophe Faure, Christophe L. Herry, Martin G. Frasch

We evaluated the effect of vagus nerve stimulation (VNS) on vagus nerve electroneurogram (VENG) and the systemic inflammatory response induced by a high dose of LPS in neonatal piglets to mimic late-onset neonatal sepsis.

Heart Rate Variability

Heart rate variability code: Does it exist and can we hack it?

no code implementations22 Jan 2020 Martin G. Frasch

Heart rate variability (HRV) has been studied for over 50 years, yet an integrative concept is missing on what HRV's mathematical properties represent physiologically.

Heart Rate Variability

Microglial memory of early life stress and inflammation: susceptibility to neurodegeneration in adulthood

no code implementations1 Jan 2019 Paula Desplats, Ashley M. Gutierrez, Marta C. Antonelli, Martin G. Frasch

We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding of this fundamental process.

Unexpected sawtooth artifact in beat-to-beat pulse transit time measured from patient monitor data

no code implementations27 Aug 2018 Yu-Ting Lin, Yu-Lun Lo, Chen-Yun Lin, Hau-Tieng Wu, Martin G. Frasch

However, in this setup the data calibration issue is often not discussed and, rather, implicitly assumed, while the clinical monitors might not be designed for the data analysis purpose.

Photoplethysmography (PPG)

Can a composite heart rate variability biomarker shed new insights about autism spectrum disorder in school-aged children?

1 code implementation24 Aug 2018 Martin G. Frasch, Chao Shen, Hau-Tieng Wu, Alexander Mueller, Emily Neuhaus, Raphael A. Bernier, Dana Kamara, Theodore P. Beauchaine

High-frequency heart rate variability (HRV) has identified parasympathetic nervous system alterations in autism spectrum disorder (ASD).

Quantitative Methods Neurons and Cognition

Efficient fetal-maternal ECG signal separation from two channel maternal abdominal ECG via diffusion-based channel selection

no code implementations7 Feb 2017 Ruilin Li, Martin G. Frasch, Hau-Tieng Wu

There is a need for affordable, widely deployable maternal-fetal ECG monitors to improve maternal and fetal health during pregnancy and delivery.

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